Lactoferrin: A Glycoprotein Involved in Immunomodulation, Anticancer, and Antimicrobial Processes
Lactoferrin is an iron binding glycoprotein with multiple roles in the body. Its participation in apoptotic processes in cancer cells, its ability to modulate various reactions of the immune system, and its activity against a broad spectrum of pathogenic microorganisms, including respiratory viruses...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-01-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/26/1/205 |
| _version_ | 1797542538660282368 |
|---|---|
| author | Quintín Rascón-Cruz Edward A. Espinoza-Sánchez Tania S. Siqueiros-Cendón Sayuri I. Nakamura-Bencomo Sigifredo Arévalo-Gallegos Blanca F. Iglesias-Figueroa |
| author_facet | Quintín Rascón-Cruz Edward A. Espinoza-Sánchez Tania S. Siqueiros-Cendón Sayuri I. Nakamura-Bencomo Sigifredo Arévalo-Gallegos Blanca F. Iglesias-Figueroa |
| author_sort | Quintín Rascón-Cruz |
| collection | DOAJ |
| description | Lactoferrin is an iron binding glycoprotein with multiple roles in the body. Its participation in apoptotic processes in cancer cells, its ability to modulate various reactions of the immune system, and its activity against a broad spectrum of pathogenic microorganisms, including respiratory viruses, have made it a protein of broad interest in pharmaceutical and food research and industry. In this review, we have focused on describing the most important functions of lactoferrin and the possible mechanisms of action that lead to its function. |
| first_indexed | 2024-03-10T13:31:59Z |
| format | Article |
| id | doaj.art-7d3c87e512474a8e87cb667917a9ff78 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T13:31:59Z |
| publishDate | 2021-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-7d3c87e512474a8e87cb667917a9ff782023-11-21T07:55:00ZengMDPI AGMolecules1420-30492021-01-0126120510.3390/molecules26010205Lactoferrin: A Glycoprotein Involved in Immunomodulation, Anticancer, and Antimicrobial ProcessesQuintín Rascón-Cruz0Edward A. Espinoza-Sánchez1Tania S. Siqueiros-Cendón2Sayuri I. Nakamura-Bencomo3Sigifredo Arévalo-Gallegos4Blanca F. Iglesias-Figueroa5Laboratorio de Biotecnología I, Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Circuito Universitario s/n Campus Universitario 2, Chihuahua C.P. 31125, MexicoLaboratorio de Biotecnología I, Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Circuito Universitario s/n Campus Universitario 2, Chihuahua C.P. 31125, MexicoLaboratorio de Biotecnología I, Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Circuito Universitario s/n Campus Universitario 2, Chihuahua C.P. 31125, MexicoLaboratorio de Biotecnología I, Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Circuito Universitario s/n Campus Universitario 2, Chihuahua C.P. 31125, MexicoLaboratorio de Biotecnología I, Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Circuito Universitario s/n Campus Universitario 2, Chihuahua C.P. 31125, MexicoLaboratorio de Biotecnología I, Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Circuito Universitario s/n Campus Universitario 2, Chihuahua C.P. 31125, MexicoLactoferrin is an iron binding glycoprotein with multiple roles in the body. Its participation in apoptotic processes in cancer cells, its ability to modulate various reactions of the immune system, and its activity against a broad spectrum of pathogenic microorganisms, including respiratory viruses, have made it a protein of broad interest in pharmaceutical and food research and industry. In this review, we have focused on describing the most important functions of lactoferrin and the possible mechanisms of action that lead to its function.https://www.mdpi.com/1420-3049/26/1/205lactoferrinimmune systemanti-cancer activityantibacterial activity |
| spellingShingle | Quintín Rascón-Cruz Edward A. Espinoza-Sánchez Tania S. Siqueiros-Cendón Sayuri I. Nakamura-Bencomo Sigifredo Arévalo-Gallegos Blanca F. Iglesias-Figueroa Lactoferrin: A Glycoprotein Involved in Immunomodulation, Anticancer, and Antimicrobial Processes Molecules lactoferrin immune system anti-cancer activity antibacterial activity |
| title | Lactoferrin: A Glycoprotein Involved in Immunomodulation, Anticancer, and Antimicrobial Processes |
| title_full | Lactoferrin: A Glycoprotein Involved in Immunomodulation, Anticancer, and Antimicrobial Processes |
| title_fullStr | Lactoferrin: A Glycoprotein Involved in Immunomodulation, Anticancer, and Antimicrobial Processes |
| title_full_unstemmed | Lactoferrin: A Glycoprotein Involved in Immunomodulation, Anticancer, and Antimicrobial Processes |
| title_short | Lactoferrin: A Glycoprotein Involved in Immunomodulation, Anticancer, and Antimicrobial Processes |
| title_sort | lactoferrin a glycoprotein involved in immunomodulation anticancer and antimicrobial processes |
| topic | lactoferrin immune system anti-cancer activity antibacterial activity |
| url | https://www.mdpi.com/1420-3049/26/1/205 |
| work_keys_str_mv | AT quintinrasconcruz lactoferrinaglycoproteininvolvedinimmunomodulationanticancerandantimicrobialprocesses AT edwardaespinozasanchez lactoferrinaglycoproteininvolvedinimmunomodulationanticancerandantimicrobialprocesses AT taniassiqueiroscendon lactoferrinaglycoproteininvolvedinimmunomodulationanticancerandantimicrobialprocesses AT sayuriinakamurabencomo lactoferrinaglycoproteininvolvedinimmunomodulationanticancerandantimicrobialprocesses AT sigifredoarevalogallegos lactoferrinaglycoproteininvolvedinimmunomodulationanticancerandantimicrobialprocesses AT blancafiglesiasfigueroa lactoferrinaglycoproteininvolvedinimmunomodulationanticancerandantimicrobialprocesses |