A Perspective: Challenges in Dementia Research
Although dementia is a common and devastating disease that has been studied intensely for more than 100 years, no effective disease modifying treatment has been found. At this impasse, new approaches are important. The purpose of this paper is to provide, in the context of current research, one clin...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/58/10/1368 |
| _version_ | 1797471657454993408 |
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| author | Mark Stecker |
| author_facet | Mark Stecker |
| author_sort | Mark Stecker |
| collection | DOAJ |
| description | Although dementia is a common and devastating disease that has been studied intensely for more than 100 years, no effective disease modifying treatment has been found. At this impasse, new approaches are important. The purpose of this paper is to provide, in the context of current research, one clinician’s perspective regarding important challenges in the field in the form of specific challenges. These challenges not only illustrate the scope of the problems inherent in finding treatments for dementia, but can also be specific targets to foster discussion, criticism and new research. One common theme is the need to transform research activities from small projects in individual laboratories/clinics to larger multinational projects, in which each clinician and researcher works as an integral part. This transformation will require collaboration between researchers, large corporations, regulatory/governmental authorities and the general population, as well as significant financial investments. However, the costs of transforming the approach are small in comparison with the cost of dementia. |
| first_indexed | 2024-03-09T19:51:16Z |
| format | Article |
| id | doaj.art-7d3f502c71244d448196fadf77a251e3 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-09T19:51:16Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-7d3f502c71244d448196fadf77a251e32023-11-24T01:09:56ZengMDPI AGMedicina1010-660X1648-91442022-09-015810136810.3390/medicina58101368A Perspective: Challenges in Dementia ResearchMark Stecker0Fresno Institute of Neuroscience, Fresno, CA 93720, USAAlthough dementia is a common and devastating disease that has been studied intensely for more than 100 years, no effective disease modifying treatment has been found. At this impasse, new approaches are important. The purpose of this paper is to provide, in the context of current research, one clinician’s perspective regarding important challenges in the field in the form of specific challenges. These challenges not only illustrate the scope of the problems inherent in finding treatments for dementia, but can also be specific targets to foster discussion, criticism and new research. One common theme is the need to transform research activities from small projects in individual laboratories/clinics to larger multinational projects, in which each clinician and researcher works as an integral part. This transformation will require collaboration between researchers, large corporations, regulatory/governmental authorities and the general population, as well as significant financial investments. However, the costs of transforming the approach are small in comparison with the cost of dementia.https://www.mdpi.com/1648-9144/58/10/1368dementiaAlzheimer’s diseasebig dataneurophysiologyimagingbiomarkers |
| spellingShingle | Mark Stecker A Perspective: Challenges in Dementia Research Medicina dementia Alzheimer’s disease big data neurophysiology imaging biomarkers |
| title | A Perspective: Challenges in Dementia Research |
| title_full | A Perspective: Challenges in Dementia Research |
| title_fullStr | A Perspective: Challenges in Dementia Research |
| title_full_unstemmed | A Perspective: Challenges in Dementia Research |
| title_short | A Perspective: Challenges in Dementia Research |
| title_sort | perspective challenges in dementia research |
| topic | dementia Alzheimer’s disease big data neurophysiology imaging biomarkers |
| url | https://www.mdpi.com/1648-9144/58/10/1368 |
| work_keys_str_mv | AT markstecker aperspectivechallengesindementiaresearch AT markstecker perspectivechallengesindementiaresearch |