Effect of Denosumab on Peripheral Compartmental Bone Density, Microarchitecture and Estimated Bone Strength in De Novo Kidney Transplant Recipients

Effect of Denosumab on Peripheral Compartmental Bone Density, Microarchitecture and Estimated Bone Strength in De Novo Kidney Transplant Recipients

Background/Aims: In a randomized controlled clinical trial in kidney transplant recipients (NCT01377467) we have recently shown that RANKL inhibition with denosumab significantly improved areal bone mineral density (aBMD) when given during the first year after transplantation. The effect of denosuma...

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Bibliographic Details
Main Authors: Marco Bonani, Ursina Meyer, Diana Frey, Nicole Graf, Heike A. Bischoff-Ferrari, Rudolf P. Wüthrich
Format: Article
Language:English
Published: Karger Publishers 2016-09-01
Series:Kidney & Blood Pressure Research
Subjects:
Dual energy X-ray absorptiometry (DXA)
Denosumab
High-resolution peripheral quantitative computed tomography (HRpQCT)
Kidney transplantation
Osteoporosis
Online Access:http://www.karger.com/Article/FullText/447930

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