Reproducible Bioinformatics Analysis Workflows for Detecting <i>IGH</i> Gene Fusions in B-Cell Acute Lymphoblastic Leukaemia Patients

Reproducible Bioinformatics Analysis Workflows for Detecting <i>IGH</i> Gene Fusions in B-Cell Acute Lymphoblastic Leukaemia Patients

B-cell acute lymphoblastic leukaemia (B-ALL) is characterised by diverse genomic alterations, the most frequent being gene fusions detected via transcriptomic analysis (mRNA-seq). Due to its hypervariable nature, gene fusions involving the Immunoglobulin Heavy Chain (<i>IGH</i>) locus ca...

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Bibliographic Details
Main Authors: Ashlee J. Thomson, Jacqueline A. Rehn, Susan L. Heatley, Laura N. Eadie, Elyse C. Page, Caitlin Schutz, Barbara J. McClure, Rosemary Sutton, Luciano Dalla-Pozza, Andrew S. Moore, Matthew Greenwood, Rishi S. Kotecha, Chun Y. Fong, Agnes S. M. Yong, David T. Yeung, James Breen, Deborah L. White
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cancers
Subjects:
B-cell acute lymphoblastic leukaemia
<i>IGH</i>
gene fusion
workflow
Online Access:https://www.mdpi.com/2072-6694/15/19/4731

Internet

https://www.mdpi.com/2072-6694/15/19/4731

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