Synthesis of new multitope tetrazole-containing ligands
Drawing the experience of 5-phenyl- and 5-pyridyltetrazoles, it was shown that classical nitration-reduction methods in combination with typical alkylation reactions of tetrazole derivatives can be used to obtain multitopic polynuclear tetrazole-containing ligands. Methods for the preparation of a n...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | Belarusian |
| Published: |
Belarusian State University
2022-08-01
|
| Series: | Журнал Белорусского государственного университета: Химия |
| Subjects: | |
| Online Access: | https://journals.bsu.by/index.php/chemistry/article/view/4739 |
| _version_ | 1798031141125488640 |
|---|---|
| author | Evgeny Y. Grigoriev Ludmila S. Ivashkevich Alexander S. Lyakhov Inna M. Grigorieva Yuri V. Grigoriev Oleg A. Ivashkevich |
| author_facet | Evgeny Y. Grigoriev Ludmila S. Ivashkevich Alexander S. Lyakhov Inna M. Grigorieva Yuri V. Grigoriev Oleg A. Ivashkevich |
| author_sort | Evgeny Y. Grigoriev |
| collection | DOAJ |
| description | Drawing the experience of 5-phenyl- and 5-pyridyltetrazoles, it was shown that classical nitration-reduction methods in combination with typical alkylation reactions of tetrazole derivatives can be used to obtain multitopic polynuclear tetrazole-containing ligands. Methods for the preparation of a number of previously undescribed polynuclear tetrazole derivatives, including those combining both tetrazole and pyridine rings in the molecule, have been developed. The composition and structure of the obtained compounds were determined by elemental analysis, single crystal X-ray diffraction, NMR and IR spectroscopy. For (5-(pyridin-2-yl)tetrazol-2-yl)(5-(pyridin-2-yl)tetrazol-1-yl)methane the crystalline structure was determined and it was found that this compound forms a 3D polymer framework due to non-classical hydrogen bonds. In its crystal structure there is a network of π – π stacking interactions between tetrazole rings of neighbouring molecules, as well as between pyridine rings. |
| first_indexed | 2024-04-11T19:52:48Z |
| format | Article |
| id | doaj.art-7d44cbc30e1e467aa098f26adae9d509 |
| institution | Directory Open Access Journal |
| issn | 2520-257X 2617-3980 |
| language | Belarusian |
| last_indexed | 2024-04-11T19:52:48Z |
| publishDate | 2022-08-01 |
| publisher | Belarusian State University |
| record_format | Article |
| series | Журнал Белорусского государственного университета: Химия |
| spelling | doaj.art-7d44cbc30e1e467aa098f26adae9d5092022-12-22T04:06:16ZbelBelarusian State UniversityЖурнал Белорусского государственного университета: Химия2520-257X2617-39802022-08-012192910.33581/2520-257X-2022-2-19-294739Synthesis of new multitope tetrazole-containing ligandsEvgeny Y. Grigoriev0Ludmila S. Ivashkevich1Alexander S. Lyakhov2Inna M. Grigorieva3Yuri V. Grigoriev4https://orcid.org/0000-0002-8153-835XOleg A. Ivashkevich5Research Institute for Physical Chemical Problems, Belarusian State University, 14 Lieninhradskaja Street, Minsk 220006, BelarusResearch Institute for Physical Chemical Problems, Belarusian State University, 14 Lieninhradskaja Street, Minsk 220006, BelarusResearch Institute for Physical Chemical Problems, Belarusian State University, 14 Lieninhradskaja Street, Minsk 220006, BelarusResearch Institute for Physical Chemical Problems, Belarusian State University, 14 Lieninhradskaja Street, Minsk 220006, BelarusResearch Institute for Physical Chemical Problems, Belarusian State University, 14 Lieninhradskaja Street, Minsk 220006, BelarusResearch Institute for Physical Chemical Problems, Belarusian State University, 14 Lieninhradskaja Street, Minsk 220006, BelarusDrawing the experience of 5-phenyl- and 5-pyridyltetrazoles, it was shown that classical nitration-reduction methods in combination with typical alkylation reactions of tetrazole derivatives can be used to obtain multitopic polynuclear tetrazole-containing ligands. Methods for the preparation of a number of previously undescribed polynuclear tetrazole derivatives, including those combining both tetrazole and pyridine rings in the molecule, have been developed. The composition and structure of the obtained compounds were determined by elemental analysis, single crystal X-ray diffraction, NMR and IR spectroscopy. For (5-(pyridin-2-yl)tetrazol-2-yl)(5-(pyridin-2-yl)tetrazol-1-yl)methane the crystalline structure was determined and it was found that this compound forms a 3D polymer framework due to non-classical hydrogen bonds. In its crystal structure there is a network of π – π stacking interactions between tetrazole rings of neighbouring molecules, as well as between pyridine rings.https://journals.bsu.by/index.php/chemistry/article/view/47395-substituted tetrazolesfunctionalisationpolynuclear derivativessynthesissingle crystal x-ray diffractionnmr spectroscopyir spectroscopy |
| spellingShingle | Evgeny Y. Grigoriev Ludmila S. Ivashkevich Alexander S. Lyakhov Inna M. Grigorieva Yuri V. Grigoriev Oleg A. Ivashkevich Synthesis of new multitope tetrazole-containing ligands Журнал Белорусского государственного университета: Химия 5-substituted tetrazoles functionalisation polynuclear derivatives synthesis single crystal x-ray diffraction nmr spectroscopy ir spectroscopy |
| title | Synthesis of new multitope tetrazole-containing ligands |
| title_full | Synthesis of new multitope tetrazole-containing ligands |
| title_fullStr | Synthesis of new multitope tetrazole-containing ligands |
| title_full_unstemmed | Synthesis of new multitope tetrazole-containing ligands |
| title_short | Synthesis of new multitope tetrazole-containing ligands |
| title_sort | synthesis of new multitope tetrazole containing ligands |
| topic | 5-substituted tetrazoles functionalisation polynuclear derivatives synthesis single crystal x-ray diffraction nmr spectroscopy ir spectroscopy |
| url | https://journals.bsu.by/index.php/chemistry/article/view/4739 |
| work_keys_str_mv | AT evgenyygrigoriev synthesisofnewmultitopetetrazolecontainingligands AT ludmilasivashkevich synthesisofnewmultitopetetrazolecontainingligands AT alexanderslyakhov synthesisofnewmultitopetetrazolecontainingligands AT innamgrigorieva synthesisofnewmultitopetetrazolecontainingligands AT yurivgrigoriev synthesisofnewmultitopetetrazolecontainingligands AT olegaivashkevich synthesisofnewmultitopetetrazolecontainingligands |