eRNA profiling uncovers the enhancer landscape of oesophageal adenocarcinoma and reveals new deregulated pathways
Cancer is driven by both genetic and epigenetic changes that impact on gene expression profiles and the resulting tumourigenic phenotype. Enhancers are transcriptional regulatory elements that are key to our understanding of how this rewiring of gene expression is achieved in cancer cells. Here, we...
Main Authors: | Ibrahim Ahmed, Shen-Hsi Yang, Samuel Ogden, Wei Zhang, Yaoyong Li, The OCCAMs consortium, Andrew D Sharrocks |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2023-02-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/80840 |
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