Transcatheter Mitral Valve Repair for Failed Surgical Mitral Valve Repair: A Systematic Review and Meta-Analysis
Objectives: To assess the outcomes of transcatheter mitral valve repair (TMVr) for failed previous surgical mitral valve repair (MVr). Methods: We searched Pubmed, Embase, and Cochrane Library databases for studies that reported the outcomes of TMVr for failed initial surgical MVr. Data were extract...
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| Format: | Article |
| Language: | English |
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IMR Press
2022-09-01
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| Series: | Reviews in Cardiovascular Medicine |
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| Online Access: | https://www.imrpress.com/journal/RCM/23/10/10.31083/j.rcm2310332 |
| _version_ | 1798029037937885184 |
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| author | Hang Xu Wu Song Sheng Liu Zhaoji Zhong |
| author_facet | Hang Xu Wu Song Sheng Liu Zhaoji Zhong |
| author_sort | Hang Xu |
| collection | DOAJ |
| description | Objectives: To assess the outcomes of transcatheter mitral valve repair (TMVr) for failed previous surgical mitral valve repair (MVr). Methods: We searched Pubmed, Embase, and Cochrane Library databases for studies that reported the outcomes of TMVr for failed initial surgical MVr. Data were extracted by 2 independent investigators and subjected to meta-analysis. The 95% confidence interval (CI) was calculated for preoperative demographics, peri-operative outcomes, and follow-up outcomes using binary and continuous data from single-arm studies. Results: Eight single-arm studies were included, with a total of 212 patients, and mean follow-up ranged from 1.0 to 15.9 months. The pooled rate of residual procedural mitral regurgitation ≤mild was 76% (95% CI: 67%~84%; I2 = 0%; 7 studies, 199 patients). During follow-up, mitral regurgitation ≤mild was found in 68% of patients (95% CI: 52%~82%; I2 = 57%; 6 studies, 147 patients). Follow-up survival was 94% (95% CI: 88%~98%; I2 = 0%; 7 studies, 196 patients). 83% patients (95% CI: 75%~89%; I2 = 47%; 6 studies, 148 patients) were in NYHA class I or II. Conclusions: TMVr for failed surgical MVr was safe and effective, which should be recommended in selected patients if technically feasible. |
| first_indexed | 2024-04-11T19:18:40Z |
| format | Article |
| id | doaj.art-7d4af061f46040dcb7dc75773824d248 |
| institution | Directory Open Access Journal |
| issn | 1530-6550 |
| language | English |
| last_indexed | 2024-04-11T19:18:40Z |
| publishDate | 2022-09-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Reviews in Cardiovascular Medicine |
| spelling | doaj.art-7d4af061f46040dcb7dc75773824d2482022-12-22T04:07:22ZengIMR PressReviews in Cardiovascular Medicine1530-65502022-09-01231033210.31083/j.rcm2310332S1530-6550(22)00686-XTranscatheter Mitral Valve Repair for Failed Surgical Mitral Valve Repair: A Systematic Review and Meta-AnalysisHang Xu0Wu Song1Sheng Liu2Zhaoji Zhong3Department of Cardiovascular Surgery, Fuwai Hospital, National Clinical Research Center for Cardiovascular Diseases, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Chinese Academy of Medical Science, 100037 Beijing, ChinaDepartment of Cardiovascular Surgery, Fuwai Hospital, National Clinical Research Center for Cardiovascular Diseases, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Chinese Academy of Medical Science, 100037 Beijing, ChinaDepartment of Cardiovascular Surgery, Fuwai Hospital, National Clinical Research Center for Cardiovascular Diseases, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Chinese Academy of Medical Science, 100037 Beijing, ChinaDepartment of Cardiovascular Surgery, Fuwai Hospital, National Clinical Research Center for Cardiovascular Diseases, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Chinese Academy of Medical Science, 100037 Beijing, ChinaObjectives: To assess the outcomes of transcatheter mitral valve repair (TMVr) for failed previous surgical mitral valve repair (MVr). Methods: We searched Pubmed, Embase, and Cochrane Library databases for studies that reported the outcomes of TMVr for failed initial surgical MVr. Data were extracted by 2 independent investigators and subjected to meta-analysis. The 95% confidence interval (CI) was calculated for preoperative demographics, peri-operative outcomes, and follow-up outcomes using binary and continuous data from single-arm studies. Results: Eight single-arm studies were included, with a total of 212 patients, and mean follow-up ranged from 1.0 to 15.9 months. The pooled rate of residual procedural mitral regurgitation ≤mild was 76% (95% CI: 67%~84%; I2 = 0%; 7 studies, 199 patients). During follow-up, mitral regurgitation ≤mild was found in 68% of patients (95% CI: 52%~82%; I2 = 57%; 6 studies, 147 patients). Follow-up survival was 94% (95% CI: 88%~98%; I2 = 0%; 7 studies, 196 patients). 83% patients (95% CI: 75%~89%; I2 = 47%; 6 studies, 148 patients) were in NYHA class I or II. Conclusions: TMVr for failed surgical MVr was safe and effective, which should be recommended in selected patients if technically feasible.https://www.imrpress.com/journal/RCM/23/10/10.31083/j.rcm2310332mitral valve repairfailurerecurrencetranscatheter mitral valve repairmitraclipneochord |
| spellingShingle | Hang Xu Wu Song Sheng Liu Zhaoji Zhong Transcatheter Mitral Valve Repair for Failed Surgical Mitral Valve Repair: A Systematic Review and Meta-Analysis Reviews in Cardiovascular Medicine mitral valve repair failure recurrence transcatheter mitral valve repair mitraclip neochord |
| title | Transcatheter Mitral Valve Repair for Failed Surgical Mitral Valve Repair: A Systematic Review and Meta-Analysis |
| title_full | Transcatheter Mitral Valve Repair for Failed Surgical Mitral Valve Repair: A Systematic Review and Meta-Analysis |
| title_fullStr | Transcatheter Mitral Valve Repair for Failed Surgical Mitral Valve Repair: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Transcatheter Mitral Valve Repair for Failed Surgical Mitral Valve Repair: A Systematic Review and Meta-Analysis |
| title_short | Transcatheter Mitral Valve Repair for Failed Surgical Mitral Valve Repair: A Systematic Review and Meta-Analysis |
| title_sort | transcatheter mitral valve repair for failed surgical mitral valve repair a systematic review and meta analysis |
| topic | mitral valve repair failure recurrence transcatheter mitral valve repair mitraclip neochord |
| url | https://www.imrpress.com/journal/RCM/23/10/10.31083/j.rcm2310332 |
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