OView-AI Supporter for Classifying Pneumonia, Pneumothorax, Tuberculosis, Lung Cancer Chest X-ray Images Using Multi-Stage Superpixels Classification

The deep learning approach has recently attracted much attention for its outstanding performance to assist in clinical diagnostic tasks, notably in computer-aided solutions. Computer-aided solutions are being developed using chest radiography to identify lung diseases. A chest X-ray image is one of...

Full description

Bibliographic Details
Main Authors: Joonho Oh, Chanho Park, Hongchang Lee, Beanbonyka Rim, Younggyu Kim, Min Hong, Jiwon Lyu, Suha Han, Seongjun Choi
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/13/9/1519
_version_ 1797602848378191872
author Joonho Oh
Chanho Park
Hongchang Lee
Beanbonyka Rim
Younggyu Kim
Min Hong
Jiwon Lyu
Suha Han
Seongjun Choi
author_facet Joonho Oh
Chanho Park
Hongchang Lee
Beanbonyka Rim
Younggyu Kim
Min Hong
Jiwon Lyu
Suha Han
Seongjun Choi
author_sort Joonho Oh
collection DOAJ
description The deep learning approach has recently attracted much attention for its outstanding performance to assist in clinical diagnostic tasks, notably in computer-aided solutions. Computer-aided solutions are being developed using chest radiography to identify lung diseases. A chest X-ray image is one of the most often utilized diagnostic imaging modalities in computer-aided solutions since it produces non-invasive standard-of-care data. However, the accurate identification of a specific illness in chest X-ray images still poses a challenge due to their high inter-class similarities and low intra-class variant abnormalities, especially given the complex nature of radiographs and the complex anatomy of the chest. In this paper, we proposed a deep-learning-based solution to classify four lung diseases (pneumonia, pneumothorax, tuberculosis, and lung cancer) and healthy lungs using chest X-ray images. In order to achieve a high performance, the EfficientNet B7 model with the pre-trained weights of ImageNet trained by Noisy Student was used as a backbone model, followed by our proposed fine-tuned layers and hyperparameters. Our study achieved an average test accuracy of 97.42%, sensitivity of 95.93%, and specificity of 99.05%. Additionally, our findings were utilized as diagnostic supporting software in OView-AI system (computer-aided application). We conducted 910 clinical trials and achieved an AUC confidence interval (95% CI) of the diagnostic results in the OView-AI system of 97.01%, sensitivity of 95.68%, and specificity of 99.34%.
first_indexed 2024-03-11T04:21:13Z
format Article
id doaj.art-7d4ba7f86d6a44769f17b73ef87c1d00
institution Directory Open Access Journal
issn 2075-4418
language English
last_indexed 2024-03-11T04:21:13Z
publishDate 2023-04-01
publisher MDPI AG
record_format Article
series Diagnostics
spelling doaj.art-7d4ba7f86d6a44769f17b73ef87c1d002023-11-17T22:44:46ZengMDPI AGDiagnostics2075-44182023-04-01139151910.3390/diagnostics13091519OView-AI Supporter for Classifying Pneumonia, Pneumothorax, Tuberculosis, Lung Cancer Chest X-ray Images Using Multi-Stage Superpixels ClassificationJoonho Oh0Chanho Park1Hongchang Lee2Beanbonyka Rim3Younggyu Kim4Min Hong5Jiwon Lyu6Suha Han7Seongjun Choi8Department of Mechanical System Engineering, Chosun University, Gwangju 61452, Republic of KoreaDepartment of Radiology, Soonchunhyang University Cheonan Hospital, Cheonan 31151, Republic of KoreaHaewootech Co., Ltd., Busan 46742, Republic of KoreaOTOM, Co., Ltd., Gwangju 61042, Republic of KoreaOTOM, Co., Ltd., Gwangju 61042, Republic of KoreaDepartment of Computer Software Engineering, Soonchunhyang University, Asan 31538, Republic of KoreaDivision of Respiratory Medicine, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan 31151, Republic of KoreaDepartment of Nursing, Soonchunhyang University Cheonan Hospital, Cheonan 31151, Republic of KoreaDepartment of Otolaryngology-Head and Neck Surgery, Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan 31151, Republic of KoreaThe deep learning approach has recently attracted much attention for its outstanding performance to assist in clinical diagnostic tasks, notably in computer-aided solutions. Computer-aided solutions are being developed using chest radiography to identify lung diseases. A chest X-ray image is one of the most often utilized diagnostic imaging modalities in computer-aided solutions since it produces non-invasive standard-of-care data. However, the accurate identification of a specific illness in chest X-ray images still poses a challenge due to their high inter-class similarities and low intra-class variant abnormalities, especially given the complex nature of radiographs and the complex anatomy of the chest. In this paper, we proposed a deep-learning-based solution to classify four lung diseases (pneumonia, pneumothorax, tuberculosis, and lung cancer) and healthy lungs using chest X-ray images. In order to achieve a high performance, the EfficientNet B7 model with the pre-trained weights of ImageNet trained by Noisy Student was used as a backbone model, followed by our proposed fine-tuned layers and hyperparameters. Our study achieved an average test accuracy of 97.42%, sensitivity of 95.93%, and specificity of 99.05%. Additionally, our findings were utilized as diagnostic supporting software in OView-AI system (computer-aided application). We conducted 910 clinical trials and achieved an AUC confidence interval (95% CI) of the diagnostic results in the OView-AI system of 97.01%, sensitivity of 95.68%, and specificity of 99.34%.https://www.mdpi.com/2075-4418/13/9/1519deep learningEfficientNetpneumoniapneumothoraxtuberculosislung cancer
spellingShingle Joonho Oh
Chanho Park
Hongchang Lee
Beanbonyka Rim
Younggyu Kim
Min Hong
Jiwon Lyu
Suha Han
Seongjun Choi
OView-AI Supporter for Classifying Pneumonia, Pneumothorax, Tuberculosis, Lung Cancer Chest X-ray Images Using Multi-Stage Superpixels Classification
Diagnostics
deep learning
EfficientNet
pneumonia
pneumothorax
tuberculosis
lung cancer
title OView-AI Supporter for Classifying Pneumonia, Pneumothorax, Tuberculosis, Lung Cancer Chest X-ray Images Using Multi-Stage Superpixels Classification
title_full OView-AI Supporter for Classifying Pneumonia, Pneumothorax, Tuberculosis, Lung Cancer Chest X-ray Images Using Multi-Stage Superpixels Classification
title_fullStr OView-AI Supporter for Classifying Pneumonia, Pneumothorax, Tuberculosis, Lung Cancer Chest X-ray Images Using Multi-Stage Superpixels Classification
title_full_unstemmed OView-AI Supporter for Classifying Pneumonia, Pneumothorax, Tuberculosis, Lung Cancer Chest X-ray Images Using Multi-Stage Superpixels Classification
title_short OView-AI Supporter for Classifying Pneumonia, Pneumothorax, Tuberculosis, Lung Cancer Chest X-ray Images Using Multi-Stage Superpixels Classification
title_sort oview ai supporter for classifying pneumonia pneumothorax tuberculosis lung cancer chest x ray images using multi stage superpixels classification
topic deep learning
EfficientNet
pneumonia
pneumothorax
tuberculosis
lung cancer
url https://www.mdpi.com/2075-4418/13/9/1519
work_keys_str_mv AT joonhooh oviewaisupporterforclassifyingpneumoniapneumothoraxtuberculosislungcancerchestxrayimagesusingmultistagesuperpixelsclassification
AT chanhopark oviewaisupporterforclassifyingpneumoniapneumothoraxtuberculosislungcancerchestxrayimagesusingmultistagesuperpixelsclassification
AT hongchanglee oviewaisupporterforclassifyingpneumoniapneumothoraxtuberculosislungcancerchestxrayimagesusingmultistagesuperpixelsclassification
AT beanbonykarim oviewaisupporterforclassifyingpneumoniapneumothoraxtuberculosislungcancerchestxrayimagesusingmultistagesuperpixelsclassification
AT younggyukim oviewaisupporterforclassifyingpneumoniapneumothoraxtuberculosislungcancerchestxrayimagesusingmultistagesuperpixelsclassification
AT minhong oviewaisupporterforclassifyingpneumoniapneumothoraxtuberculosislungcancerchestxrayimagesusingmultistagesuperpixelsclassification
AT jiwonlyu oviewaisupporterforclassifyingpneumoniapneumothoraxtuberculosislungcancerchestxrayimagesusingmultistagesuperpixelsclassification
AT suhahan oviewaisupporterforclassifyingpneumoniapneumothoraxtuberculosislungcancerchestxrayimagesusingmultistagesuperpixelsclassification
AT seongjunchoi oviewaisupporterforclassifyingpneumoniapneumothoraxtuberculosislungcancerchestxrayimagesusingmultistagesuperpixelsclassification