Generation of Synthetic Chest X-ray Images and Detection of COVID-19: A Deep Learning Based Approach

COVID-19 is a disease caused by the SARS-CoV-2 virus. The COVID-19 virus spreads when a person comes into contact with an affected individual. This is mainly through drops of saliva or nasal discharge. Most of the affected people have mild symptoms while some people develop acute respiratory distres...

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Main Authors: Yash Karbhari, Arpan Basu, Zong Woo Geem, Gi-Tae Han, Ram Sarkar
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/11/5/895
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author Yash Karbhari
Arpan Basu
Zong Woo Geem
Gi-Tae Han
Ram Sarkar
author_facet Yash Karbhari
Arpan Basu
Zong Woo Geem
Gi-Tae Han
Ram Sarkar
author_sort Yash Karbhari
collection DOAJ
description COVID-19 is a disease caused by the SARS-CoV-2 virus. The COVID-19 virus spreads when a person comes into contact with an affected individual. This is mainly through drops of saliva or nasal discharge. Most of the affected people have mild symptoms while some people develop acute respiratory distress syndrome (ARDS), which damages organs like the lungs and heart. Chest X-rays (CXRs) have been widely used to identify abnormalities that help in detecting the COVID-19 virus. They have also been used as an initial screening procedure for individuals highly suspected of being infected. However, the availability of radiographic CXRs is still scarce. This can limit the performance of deep learning (DL) based approaches for COVID-19 detection. To overcome these limitations, in this work, we developed an Auxiliary Classifier Generative Adversarial Network (ACGAN), to generate CXRs. Each generated X-ray belongs to one of the two classes COVID-19 positive or normal. To ensure the goodness of the synthetic images, we performed some experimentation on the obtained images using the latest Convolutional Neural Networks (CNNs) to detect COVID-19 in the CXRs. We fine-tuned the models and achieved more than 98% accuracy. After that, we also performed feature selection using the Harmony Search (HS) algorithm, which reduces the number of features while retaining classification accuracy. We further release a GAN-generated dataset consisting of 500 COVID-19 radiographic images.
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spelling doaj.art-7d4c409c01e24cfeba05c2f5543f81602023-11-21T20:11:20ZengMDPI AGDiagnostics2075-44182021-05-0111589510.3390/diagnostics11050895Generation of Synthetic Chest X-ray Images and Detection of COVID-19: A Deep Learning Based ApproachYash Karbhari0Arpan Basu1Zong Woo Geem2Gi-Tae Han3Ram Sarkar4Department of Information Technology, Pune Vidyarthi Griha’s College of Engineering and Technology, Pune 411009, IndiaDepartment of Computer Science and Engineering, Jadavpur University, Kolkata 700032, IndiaCollege of IT Convergence, Gachon University, 1342 Seongnam Daero, Seongnam 13120, KoreaCollege of IT Convergence, Gachon University, 1342 Seongnam Daero, Seongnam 13120, KoreaDepartment of Computer Science and Engineering, Jadavpur University, Kolkata 700032, IndiaCOVID-19 is a disease caused by the SARS-CoV-2 virus. The COVID-19 virus spreads when a person comes into contact with an affected individual. This is mainly through drops of saliva or nasal discharge. Most of the affected people have mild symptoms while some people develop acute respiratory distress syndrome (ARDS), which damages organs like the lungs and heart. Chest X-rays (CXRs) have been widely used to identify abnormalities that help in detecting the COVID-19 virus. They have also been used as an initial screening procedure for individuals highly suspected of being infected. However, the availability of radiographic CXRs is still scarce. This can limit the performance of deep learning (DL) based approaches for COVID-19 detection. To overcome these limitations, in this work, we developed an Auxiliary Classifier Generative Adversarial Network (ACGAN), to generate CXRs. Each generated X-ray belongs to one of the two classes COVID-19 positive or normal. To ensure the goodness of the synthetic images, we performed some experimentation on the obtained images using the latest Convolutional Neural Networks (CNNs) to detect COVID-19 in the CXRs. We fine-tuned the models and achieved more than 98% accuracy. After that, we also performed feature selection using the Harmony Search (HS) algorithm, which reduces the number of features while retaining classification accuracy. We further release a GAN-generated dataset consisting of 500 COVID-19 radiographic images.https://www.mdpi.com/2075-4418/11/5/895COVID-19 detectiongenerative adversarial networksynthetic data generationharmony searchfeature selectionchest X-ray
spellingShingle Yash Karbhari
Arpan Basu
Zong Woo Geem
Gi-Tae Han
Ram Sarkar
Generation of Synthetic Chest X-ray Images and Detection of COVID-19: A Deep Learning Based Approach
Diagnostics
COVID-19 detection
generative adversarial network
synthetic data generation
harmony search
feature selection
chest X-ray
title Generation of Synthetic Chest X-ray Images and Detection of COVID-19: A Deep Learning Based Approach
title_full Generation of Synthetic Chest X-ray Images and Detection of COVID-19: A Deep Learning Based Approach
title_fullStr Generation of Synthetic Chest X-ray Images and Detection of COVID-19: A Deep Learning Based Approach
title_full_unstemmed Generation of Synthetic Chest X-ray Images and Detection of COVID-19: A Deep Learning Based Approach
title_short Generation of Synthetic Chest X-ray Images and Detection of COVID-19: A Deep Learning Based Approach
title_sort generation of synthetic chest x ray images and detection of covid 19 a deep learning based approach
topic COVID-19 detection
generative adversarial network
synthetic data generation
harmony search
feature selection
chest X-ray
url https://www.mdpi.com/2075-4418/11/5/895
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