Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil
We report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most p...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Fundação Oswaldo Cruz (FIOCRUZ)
2004-05-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000300007 |
| _version_ | 1797703048503492608 |
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| author | Márcio R Cruz Daniela M Cerqueira Waldenor B Cruz Geni NL Camara Marcelo M Brígido Evandro O Silva Luciano GS Carvalho Cláudia RF Martins |
| author_facet | Márcio R Cruz Daniela M Cerqueira Waldenor B Cruz Geni NL Camara Marcelo M Brígido Evandro O Silva Luciano GS Carvalho Cláudia RF Martins |
| author_sort | Márcio R Cruz |
| collection | DOAJ |
| description | We report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most prevalent HPV-16 variant was the European (50%), followed by Asian-American (41.2%), African-1 (5.9%), and African-2 (2.9%). European and non-European variants appeared in equal frequencies among the cytological types of lesions - atypical squamous or glandular cells of undetermined significance, cytological alterations suggesting HPV infection, cervical intraepithelial neoplasias, squamous cell carcinoma, and adenocarcinoma. |
| first_indexed | 2024-03-12T04:58:46Z |
| format | Article |
| id | doaj.art-7d4e6ca0c604402f96ec5b5febb0a80e |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T04:58:46Z |
| publishDate | 2004-05-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-7d4e6ca0c604402f96ec5b5febb0a80e2023-09-03T09:14:30ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602004-05-0199328128210.1590/S0074-02762004000300007Prevalence of human papillomavirus type 16 variants in the Federal District, Central BrazilMárcio R CruzDaniela M CerqueiraWaldenor B CruzGeni NL CamaraMarcelo M BrígidoEvandro O SilvaLuciano GS CarvalhoCláudia RF MartinsWe report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most prevalent HPV-16 variant was the European (50%), followed by Asian-American (41.2%), African-1 (5.9%), and African-2 (2.9%). European and non-European variants appeared in equal frequencies among the cytological types of lesions - atypical squamous or glandular cells of undetermined significance, cytological alterations suggesting HPV infection, cervical intraepithelial neoplasias, squamous cell carcinoma, and adenocarcinoma.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000300007human papillomavirus type 16variantsFederal DistrictBrazil |
| spellingShingle | Márcio R Cruz Daniela M Cerqueira Waldenor B Cruz Geni NL Camara Marcelo M Brígido Evandro O Silva Luciano GS Carvalho Cláudia RF Martins Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil Memorias do Instituto Oswaldo Cruz human papillomavirus type 16 variants Federal District Brazil |
| title | Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil |
| title_full | Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil |
| title_fullStr | Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil |
| title_full_unstemmed | Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil |
| title_short | Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil |
| title_sort | prevalence of human papillomavirus type 16 variants in the federal district central brazil |
| topic | human papillomavirus type 16 variants Federal District Brazil |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762004000300007 |
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