Chance promoter activities illuminate the origins of eukaryotic intergenic transcriptions
It is debated whether the pervasive intergenic transcription from eukaryotic genomes has functional significance. Here, Xu et al. find that only 1–5% of yeast intergenic transcription is unattributable to chance promoter activity or neighboring gene expression.
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-023-37610-w |
| _version_ | 1797853724509470720 |
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| author | Haiqing Xu Chuan Li Chuan Xu Jianzhi Zhang |
| author_facet | Haiqing Xu Chuan Li Chuan Xu Jianzhi Zhang |
| author_sort | Haiqing Xu |
| collection | DOAJ |
| description | It is debated whether the pervasive intergenic transcription from eukaryotic genomes has functional significance. Here, Xu et al. find that only 1–5% of yeast intergenic transcription is unattributable to chance promoter activity or neighboring gene expression. |
| first_indexed | 2024-04-09T19:54:15Z |
| format | Article |
| id | doaj.art-7d4eaf2ff8824303af14fcf267431127 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-09T19:54:15Z |
| publishDate | 2023-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-7d4eaf2ff8824303af14fcf2674311272023-04-03T05:33:41ZengNature PortfolioNature Communications2041-17232023-04-0114111110.1038/s41467-023-37610-wChance promoter activities illuminate the origins of eukaryotic intergenic transcriptionsHaiqing Xu0Chuan Li1Chuan Xu2Jianzhi Zhang3Department of Ecology and Evolutionary Biology, University of MichiganDepartment of Ecology and Evolutionary Biology, University of MichiganDepartment of Ecology and Evolutionary Biology, University of MichiganDepartment of Ecology and Evolutionary Biology, University of MichiganIt is debated whether the pervasive intergenic transcription from eukaryotic genomes has functional significance. Here, Xu et al. find that only 1–5% of yeast intergenic transcription is unattributable to chance promoter activity or neighboring gene expression.https://doi.org/10.1038/s41467-023-37610-w |
| spellingShingle | Haiqing Xu Chuan Li Chuan Xu Jianzhi Zhang Chance promoter activities illuminate the origins of eukaryotic intergenic transcriptions Nature Communications |
| title | Chance promoter activities illuminate the origins of eukaryotic intergenic transcriptions |
| title_full | Chance promoter activities illuminate the origins of eukaryotic intergenic transcriptions |
| title_fullStr | Chance promoter activities illuminate the origins of eukaryotic intergenic transcriptions |
| title_full_unstemmed | Chance promoter activities illuminate the origins of eukaryotic intergenic transcriptions |
| title_short | Chance promoter activities illuminate the origins of eukaryotic intergenic transcriptions |
| title_sort | chance promoter activities illuminate the origins of eukaryotic intergenic transcriptions |
| url | https://doi.org/10.1038/s41467-023-37610-w |
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