Rheological and Biological Properties of Adhesive Skin Secretions from Eupsophus vertebralis (Anura: Alsodidae)

Skin secretions from Patagonian ground frogs, Eupsophus vertebralis, have previously been reported as a potent proteinaceous adhesive with potential biomedical applications. Here, we conducted a rheological analysis indicating the mechanical robustness of these secretions, with a storage modulus ran...

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Bibliographic Details
Main Authors: Felipe A. Contreras, Daniela P. Sepúlveda, André Capaldo Amaral, José J. Nuñez, Eliane Trovatti, Elkin Y. Suárez-Villota
Format: Article
Language:English
Published: Hindawi Limited 2024-01-01
Series:Scientifica
Online Access:http://dx.doi.org/10.1155/2024/2722351
Description
Summary:Skin secretions from Patagonian ground frogs, Eupsophus vertebralis, have previously been reported as a potent proteinaceous adhesive with potential biomedical applications. Here, we conducted a rheological analysis indicating the mechanical robustness of these secretions, with a storage modulus ranging from 1 to 10 Pa. In addition, antimicrobial and cytotoxicity assays were performed, revealing no antimicrobial activity against both the Gram-positive and Gram-negative bacteria. The cytotoxicity results were intriguing, as three samples showed no harm, and one exhibited a severe cytotoxic effect on the human cell line MG63. These properties, as indicated by these preliminary results, reinforce their potential for practical applications in the industrial and medical sectors.
ISSN:2090-908X