Evolution of Stereotactic Ablative Radiotherapy in Lung Cancer and Birmingham’s (UK) Experience

Stereotactic ablative radiotherapy (SABR) has taken a pivotal role in early lung cancer management particularly in the medically inoperable patients. Retrospective studies have shown this to be well tolerated with comparable results to surgery and no significant increase in toxicity. Paucity of rand...

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Main Authors: Sundus Yahya, Qamar Ghafoor, Robert Stevenson, Steven Watkins, Beshar Allos
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Medicines
Subjects:
Online Access:http://www.mdpi.com/2305-6320/5/3/77
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author Sundus Yahya
Qamar Ghafoor
Robert Stevenson
Steven Watkins
Beshar Allos
author_facet Sundus Yahya
Qamar Ghafoor
Robert Stevenson
Steven Watkins
Beshar Allos
author_sort Sundus Yahya
collection DOAJ
description Stereotactic ablative radiotherapy (SABR) has taken a pivotal role in early lung cancer management particularly in the medically inoperable patients. Retrospective studies have shown this to be well tolerated with comparable results to surgery and no significant increase in toxicity. Paucity of randomized evidence has dictated initiation of several trials to provide good quality evidence to steer future practice. This review summaries salient developments in lung SABR, comparisons to surgery and other platforms and our local experience at University Hospitals Birmingham, UK of lung SABR since its initiation in June 2013.
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spelling doaj.art-7d5516ff6da64c0bbb2ebfb36896c4dc2022-12-22T03:24:27ZengMDPI AGMedicines2305-63202018-07-01537710.3390/medicines5030077medicines5030077Evolution of Stereotactic Ablative Radiotherapy in Lung Cancer and Birmingham’s (UK) ExperienceSundus Yahya0Qamar Ghafoor1Robert Stevenson2Steven Watkins3Beshar Allos4Hall-Edwards Radiotherapy Research Group, Queen Elizabeth Hospital, Birmingham B15 2TH, UKHall-Edwards Radiotherapy Research Group, Queen Elizabeth Hospital, Birmingham B15 2TH, UKHall-Edwards Radiotherapy Research Group, Queen Elizabeth Hospital, Birmingham B15 2TH, UKHall-Edwards Radiotherapy Research Group, Queen Elizabeth Hospital, Birmingham B15 2TH, UKHall-Edwards Radiotherapy Research Group, Queen Elizabeth Hospital, Birmingham B15 2TH, UKStereotactic ablative radiotherapy (SABR) has taken a pivotal role in early lung cancer management particularly in the medically inoperable patients. Retrospective studies have shown this to be well tolerated with comparable results to surgery and no significant increase in toxicity. Paucity of randomized evidence has dictated initiation of several trials to provide good quality evidence to steer future practice. This review summaries salient developments in lung SABR, comparisons to surgery and other platforms and our local experience at University Hospitals Birmingham, UK of lung SABR since its initiation in June 2013.http://www.mdpi.com/2305-6320/5/3/77lung cancerradiotherapystereotactic ablative radiotherapy (SABR)stereotactic body radiotherapy (SBRT)radiofrequency ablation (RFA)microwave ablationdosimetryradiotherapy treatment techniques
spellingShingle Sundus Yahya
Qamar Ghafoor
Robert Stevenson
Steven Watkins
Beshar Allos
Evolution of Stereotactic Ablative Radiotherapy in Lung Cancer and Birmingham’s (UK) Experience
Medicines
lung cancer
radiotherapy
stereotactic ablative radiotherapy (SABR)
stereotactic body radiotherapy (SBRT)
radiofrequency ablation (RFA)
microwave ablation
dosimetry
radiotherapy treatment techniques
title Evolution of Stereotactic Ablative Radiotherapy in Lung Cancer and Birmingham’s (UK) Experience
title_full Evolution of Stereotactic Ablative Radiotherapy in Lung Cancer and Birmingham’s (UK) Experience
title_fullStr Evolution of Stereotactic Ablative Radiotherapy in Lung Cancer and Birmingham’s (UK) Experience
title_full_unstemmed Evolution of Stereotactic Ablative Radiotherapy in Lung Cancer and Birmingham’s (UK) Experience
title_short Evolution of Stereotactic Ablative Radiotherapy in Lung Cancer and Birmingham’s (UK) Experience
title_sort evolution of stereotactic ablative radiotherapy in lung cancer and birmingham s uk experience
topic lung cancer
radiotherapy
stereotactic ablative radiotherapy (SABR)
stereotactic body radiotherapy (SBRT)
radiofrequency ablation (RFA)
microwave ablation
dosimetry
radiotherapy treatment techniques
url http://www.mdpi.com/2305-6320/5/3/77
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