Variations in facial conformation are associated with differences in nasal microbiota in healthy dogs
Abstract Background Extrinsic and intrinsic factors have been shown to influence nasal microbiota (NM) in humans. Very few studies investigated the association between nasal microbiota and factors such as facial/body conformation, age, and environment in dogs. The objectives are to investigate varia...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-11-01
|
| Series: | BMC Veterinary Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12917-021-03055-w |
| _version_ | 1831583612774907904 |
|---|---|
| author | Vangrinsven Emilie Fastrès Aline Taminiau Bernard Frédéric Billen Daube Georges Clercx Cécile |
| author_facet | Vangrinsven Emilie Fastrès Aline Taminiau Bernard Frédéric Billen Daube Georges Clercx Cécile |
| author_sort | Vangrinsven Emilie |
| collection | DOAJ |
| description | Abstract Background Extrinsic and intrinsic factors have been shown to influence nasal microbiota (NM) in humans. Very few studies investigated the association between nasal microbiota and factors such as facial/body conformation, age, and environment in dogs. The objectives are to investigate variations in NM in healthy dogs with different facial and body conformations. A total of 46 dogs of different age, living environment and from 3 different breed groups were recruited: 22 meso−/dolichocephalic medium to large breed dogs, 12 brachycephalic dogs and 12 terrier breeds. The nasal bacterial microbiota was assessed through sequencing of 16S rRNA gene (V1-V3 regions) amplicons. Results We showed major differences in the NM composition together with increased richness and α-diversity in brachycephalic dogs, compared to meso−/dolichocephalic medium to large dogs and dogs from terrier breeds. Conclusion Healthy brachycephalic breeds and their unique facial conformation is associated with a distinct NM profile. Description of the NM in healthy dogs serves as a foundation for future researches assessing the changes associated with disease and the modulation of NM communities as a potential treatment. |
| first_indexed | 2024-12-17T20:45:13Z |
| format | Article |
| id | doaj.art-7d5574ebb0f34654bd02870b5b2c69b1 |
| institution | Directory Open Access Journal |
| issn | 1746-6148 |
| language | English |
| last_indexed | 2024-12-17T20:45:13Z |
| publishDate | 2021-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Veterinary Research |
| spelling | doaj.art-7d5574ebb0f34654bd02870b5b2c69b12022-12-21T21:33:10ZengBMCBMC Veterinary Research1746-61482021-11-0117111610.1186/s12917-021-03055-wVariations in facial conformation are associated with differences in nasal microbiota in healthy dogsVangrinsven Emilie0Fastrès Aline1Taminiau Bernard2Frédéric Billen3Daube Georges4Clercx Cécile5Department of Clinical Sciences, Faculty of Veterinary Medicine, University of LiègeDepartment of Clinical Sciences, Faculty of Veterinary Medicine, University of LiègeDepartment of Food Sciences - Microbiology, Faculty of Veterinary Medicine, University of LiègeDepartment of Clinical Sciences, Faculty of Veterinary Medicine, University of LiègeDepartment of Food Sciences - Microbiology, Faculty of Veterinary Medicine, University of LiègeDepartment of Clinical Sciences, Faculty of Veterinary Medicine, University of LiègeAbstract Background Extrinsic and intrinsic factors have been shown to influence nasal microbiota (NM) in humans. Very few studies investigated the association between nasal microbiota and factors such as facial/body conformation, age, and environment in dogs. The objectives are to investigate variations in NM in healthy dogs with different facial and body conformations. A total of 46 dogs of different age, living environment and from 3 different breed groups were recruited: 22 meso−/dolichocephalic medium to large breed dogs, 12 brachycephalic dogs and 12 terrier breeds. The nasal bacterial microbiota was assessed through sequencing of 16S rRNA gene (V1-V3 regions) amplicons. Results We showed major differences in the NM composition together with increased richness and α-diversity in brachycephalic dogs, compared to meso−/dolichocephalic medium to large dogs and dogs from terrier breeds. Conclusion Healthy brachycephalic breeds and their unique facial conformation is associated with a distinct NM profile. Description of the NM in healthy dogs serves as a foundation for future researches assessing the changes associated with disease and the modulation of NM communities as a potential treatment.https://doi.org/10.1186/s12917-021-03055-wNasal cavityMicrobiotaDogsBreedFacial conformation |
| spellingShingle | Vangrinsven Emilie Fastrès Aline Taminiau Bernard Frédéric Billen Daube Georges Clercx Cécile Variations in facial conformation are associated with differences in nasal microbiota in healthy dogs BMC Veterinary Research Nasal cavity Microbiota Dogs Breed Facial conformation |
| title | Variations in facial conformation are associated with differences in nasal microbiota in healthy dogs |
| title_full | Variations in facial conformation are associated with differences in nasal microbiota in healthy dogs |
| title_fullStr | Variations in facial conformation are associated with differences in nasal microbiota in healthy dogs |
| title_full_unstemmed | Variations in facial conformation are associated with differences in nasal microbiota in healthy dogs |
| title_short | Variations in facial conformation are associated with differences in nasal microbiota in healthy dogs |
| title_sort | variations in facial conformation are associated with differences in nasal microbiota in healthy dogs |
| topic | Nasal cavity Microbiota Dogs Breed Facial conformation |
| url | https://doi.org/10.1186/s12917-021-03055-w |
| work_keys_str_mv | AT vangrinsvenemilie variationsinfacialconformationareassociatedwithdifferencesinnasalmicrobiotainhealthydogs AT fastresaline variationsinfacialconformationareassociatedwithdifferencesinnasalmicrobiotainhealthydogs AT taminiaubernard variationsinfacialconformationareassociatedwithdifferencesinnasalmicrobiotainhealthydogs AT fredericbillen variationsinfacialconformationareassociatedwithdifferencesinnasalmicrobiotainhealthydogs AT daubegeorges variationsinfacialconformationareassociatedwithdifferencesinnasalmicrobiotainhealthydogs AT clercxcecile variationsinfacialconformationareassociatedwithdifferencesinnasalmicrobiotainhealthydogs |