Treatment of HCV infection in patients with cirrhosis
The treatment of patients with cirrhosis has the following purposes: to prevent the complications of the disease; to allow for the regression of cirrhosis; and to prevent reinfection in the graft in patients undergoing liver transplantation. When the sustained viral response is evaluated in patients...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2010-01-01
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| Series: | Annals of Hepatology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1665268119317296 |
| _version_ | 1818608230426738688 |
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| author | Angelo Alves de Mattos Ângelo Zambam de Mattos |
| author_facet | Angelo Alves de Mattos Ângelo Zambam de Mattos |
| author_sort | Angelo Alves de Mattos |
| collection | DOAJ |
| description | The treatment of patients with cirrhosis has the following purposes: to prevent the complications of the disease; to allow for the regression of cirrhosis; and to prevent reinfection in the graft in patients undergoing liver transplantation. When the sustained viral response is evaluated in patients with cirrhosis, especially in those with decompensated disease, it is noted to be lower than that of patients with chronic hepatitis, and with a higher possibility of complications of the treatment. Based on a review of the literature, we conclude that we should treat patients with compensated cirrhosis, probably also those with portal hypertension, and patients with decompensated cirrhosis only when included on the transplant list, as long as Child B with HCV genotype 2 (possibly 3) and preferably after clinical compensation. |
| first_indexed | 2024-12-16T14:39:20Z |
| format | Article |
| id | doaj.art-7d571e1186e6478db5de3a64d6f8af9c |
| institution | Directory Open Access Journal |
| issn | 1665-2681 |
| language | English |
| last_indexed | 2024-12-16T14:39:20Z |
| publishDate | 2010-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Annals of Hepatology |
| spelling | doaj.art-7d571e1186e6478db5de3a64d6f8af9c2022-12-21T22:28:00ZengElsevierAnnals of Hepatology1665-26812010-01-019S80S83Treatment of HCV infection in patients with cirrhosisAngelo Alves de Mattos0Ângelo Zambam de Mattos1Head Professor of the Department of Gastroenterology and of the Post-Graduate Course of Hepatology of Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Brazil; President of the Latin American Association for the Study of the Liver; Correspondence and reprint request:Gastroenterologist and Post-Graduate Student in Hepatology of Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), BrazilThe treatment of patients with cirrhosis has the following purposes: to prevent the complications of the disease; to allow for the regression of cirrhosis; and to prevent reinfection in the graft in patients undergoing liver transplantation. When the sustained viral response is evaluated in patients with cirrhosis, especially in those with decompensated disease, it is noted to be lower than that of patients with chronic hepatitis, and with a higher possibility of complications of the treatment. Based on a review of the literature, we conclude that we should treat patients with compensated cirrhosis, probably also those with portal hypertension, and patients with decompensated cirrhosis only when included on the transplant list, as long as Child B with HCV genotype 2 (possibly 3) and preferably after clinical compensation.http://www.sciencedirect.com/science/article/pii/S1665268119317296CirrhosisPeginterferonHepatitis C virus |
| spellingShingle | Angelo Alves de Mattos Ângelo Zambam de Mattos Treatment of HCV infection in patients with cirrhosis Annals of Hepatology Cirrhosis Peginterferon Hepatitis C virus |
| title | Treatment of HCV infection in patients with cirrhosis |
| title_full | Treatment of HCV infection in patients with cirrhosis |
| title_fullStr | Treatment of HCV infection in patients with cirrhosis |
| title_full_unstemmed | Treatment of HCV infection in patients with cirrhosis |
| title_short | Treatment of HCV infection in patients with cirrhosis |
| title_sort | treatment of hcv infection in patients with cirrhosis |
| topic | Cirrhosis Peginterferon Hepatitis C virus |
| url | http://www.sciencedirect.com/science/article/pii/S1665268119317296 |
| work_keys_str_mv | AT angeloalvesdemattos treatmentofhcvinfectioninpatientswithcirrhosis AT angelozambamdemattos treatmentofhcvinfectioninpatientswithcirrhosis |