Oral Human Papillomavirus Infection in Children during the First 6 Years of Life, Finland
Human papillomavirus (HPV) infections are found in children, but transmission modes and outcomes are incompletely understood. We evaluated oral samples from 331 children in Finland who participated in the Finnish Family HPV Study from birth during 9 follow-up visits (mean time 51.9 months). We teste...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2021-03-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/27/3/20-2721_article |
| _version_ | 1818918497021853696 |
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| author | Stina Syrjänen Marjut Rintala Marja Sarkola Jaana Willberg Jaana Rautava Hanna Koskimaa Anna Paaso Kari Syrjänen Seija Grénman Karolina Louvanto |
| author_facet | Stina Syrjänen Marjut Rintala Marja Sarkola Jaana Willberg Jaana Rautava Hanna Koskimaa Anna Paaso Kari Syrjänen Seija Grénman Karolina Louvanto |
| author_sort | Stina Syrjänen |
| collection | DOAJ |
| description | Human papillomavirus (HPV) infections are found in children, but transmission modes and outcomes are incompletely understood. We evaluated oral samples from 331 children in Finland who participated in the Finnish Family HPV Study from birth during 9 follow-up visits (mean time 51.9 months). We tested samples for 24 HPV genotypes. Oral HPV prevalence for children varied from 8.7% (at a 36-month visit) to 22.8% (at birth), and 18 HPV genotypes were identified. HPV16 was the most prevalent type to persist, followed by HPV18, HPV33, and HPV6. Persistent, oral, high-risk HPV infection for children was associated with oral HPV carriage of the mother at birth and seroconversion of the mother to high-risk HPV during follow-up (odds ratio 1.60–1.92, 95% CI 1.02–2.74). Children acquire their first oral HPV infection at an early age. The HPV status of the mother has a major impact on the outcome of oral HPV persistence for her offspring. |
| first_indexed | 2024-12-20T00:50:54Z |
| format | Article |
| id | doaj.art-7d57dd21b0d04294ab7437cb58be5573 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-20T00:50:54Z |
| publishDate | 2021-03-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-7d57dd21b0d04294ab7437cb58be55732022-12-21T19:59:15ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592021-03-0127375976610.3201/eid2703.202721Oral Human Papillomavirus Infection in Children during the First 6 Years of Life, FinlandStina SyrjänenMarjut RintalaMarja SarkolaJaana WillbergJaana RautavaHanna KoskimaaAnna PaasoKari SyrjänenSeija GrénmanKarolina LouvantoHuman papillomavirus (HPV) infections are found in children, but transmission modes and outcomes are incompletely understood. We evaluated oral samples from 331 children in Finland who participated in the Finnish Family HPV Study from birth during 9 follow-up visits (mean time 51.9 months). We tested samples for 24 HPV genotypes. Oral HPV prevalence for children varied from 8.7% (at a 36-month visit) to 22.8% (at birth), and 18 HPV genotypes were identified. HPV16 was the most prevalent type to persist, followed by HPV18, HPV33, and HPV6. Persistent, oral, high-risk HPV infection for children was associated with oral HPV carriage of the mother at birth and seroconversion of the mother to high-risk HPV during follow-up (odds ratio 1.60–1.92, 95% CI 1.02–2.74). Children acquire their first oral HPV infection at an early age. The HPV status of the mother has a major impact on the outcome of oral HPV persistence for her offspring.https://wwwnc.cdc.gov/eid/article/27/3/20-2721_articlehuman papillomavirusHPVvirusesoral infectionsexually transmitted infectionschildren |
| spellingShingle | Stina Syrjänen Marjut Rintala Marja Sarkola Jaana Willberg Jaana Rautava Hanna Koskimaa Anna Paaso Kari Syrjänen Seija Grénman Karolina Louvanto Oral Human Papillomavirus Infection in Children during the First 6 Years of Life, Finland Emerging Infectious Diseases human papillomavirus HPV viruses oral infection sexually transmitted infections children |
| title | Oral Human Papillomavirus Infection in Children during the First 6 Years of Life, Finland |
| title_full | Oral Human Papillomavirus Infection in Children during the First 6 Years of Life, Finland |
| title_fullStr | Oral Human Papillomavirus Infection in Children during the First 6 Years of Life, Finland |
| title_full_unstemmed | Oral Human Papillomavirus Infection in Children during the First 6 Years of Life, Finland |
| title_short | Oral Human Papillomavirus Infection in Children during the First 6 Years of Life, Finland |
| title_sort | oral human papillomavirus infection in children during the first 6 years of life finland |
| topic | human papillomavirus HPV viruses oral infection sexually transmitted infections children |
| url | https://wwwnc.cdc.gov/eid/article/27/3/20-2721_article |
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