EXOSC5 as a Novel Prognostic Marker Promotes Proliferation of Colorectal Cancer via Activating the ERK and AKT Pathways

EXOSC5 as a Novel Prognostic Marker Promotes Proliferation of Colorectal Cancer via Activating the ERK and AKT Pathways

Background and Objective: Exosome component 5 (EXOSC5) is a novel cancer-related gene that is aberrantly expressed in various malignances. However, the molecular mechanism and biological role of EXOSC5 have not been explored in colorectal cancer (CRC). In this study, we investigated the functions an...

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Bibliographic Details
Main Authors: Hongda Pan, Jingxin Pan, Shibo Song, Lei Ji, Hong Lv, Zhangru Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Oncology
Subjects:
EXOSC5
proliferation
colorectal cancer
Akt signaling pathway
ERK signaling pathway
prognosis
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00643/full

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