Surface Coating with Hyaluronic Acid-Gelatin-Crosslinked Hydrogel on Gelatin-Conjugated Poly(dimethylsiloxane) for Implantable Medical Device-Induced Fibrosis

Surface Coating with Hyaluronic Acid-Gelatin-Crosslinked Hydrogel on Gelatin-Conjugated Poly(dimethylsiloxane) for Implantable Medical Device-Induced Fibrosis

Polydimethylsiloxane (PDMS) is a biocompatible polymer that has been applied in many fields. However, the surface hydrophobicity of PDMS can limit successful implementation, and this must be reduced by surface modification to improve biocompatibility. In this study, we modified the PDMS surface with...

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Bibliographic Details
Main Authors: Haejin Joo, Jonghyun Park, Chanutchamon Sutthiwanjampa, Hankoo Kim, Taehui Bae, Wooseob Kim, Jinhwa Choi, Mikyung Kim, Shinhyuk Kang, Hansoo Park
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Pharmaceutics
Subjects:
polydimethylsiloxane
surface coating
hydrogel
Schiff-base reaction
hydrophilicity
biocompatibility
Online Access:https://www.mdpi.com/1999-4923/13/2/269

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