Metabolic Activation of Benzo[<i>a</i>]pyrene by Human Tissue Organoid Cultures

Metabolic Activation of Benzo[<i>a</i>]pyrene by Human Tissue Organoid Cultures

Organoids are 3D cultures that to some extent reproduce the structure, composition and function of the mammalian tissues from which they derive, thereby creating in vitro systems with more in vivo-like characteristics than 2D monocultures. Here, the ability of human organoids derived from normal gas...

Full description

Bibliographic Details
Main Authors: Angela L. Caipa Garcia, Jill E. Kucab, Halh Al-Serori, Rebekah S. S. Beck, Franziska Fischer, Matthias Hufnagel, Andrea Hartwig, Andrew Floeder, Silvia Balbo, Hayley Francies, Mathew Garnett, Meritxell Huch, Jarno Drost, Matthias Zilbauer, Volker M. Arlt, David H. Phillips
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
carcinogen
3D culture
benzo[<i>a</i>]pyrene
human tissue organoid
CYP1A1
NQO1
Online Access:https://www.mdpi.com/1422-0067/24/1/606

Similar Items

Similar Items