Discovery of inhibitors against SARS-CoV-2 associated fungal coinfections via virtual screening, ADMET evaluation, PASS, molecular docking, dynamics and pharmacophore studies

Discovery of inhibitors against SARS-CoV-2 associated fungal coinfections via virtual screening, ADMET evaluation, PASS, molecular docking, dynamics and pharmacophore studies

The black fungus is a SARS-CoV-2-associated fungal co-infection. Mechanisms by which antifungal drugs act against Mucormycosis are by inhibition of enzymes implicated in ergosterol biosynthesis or cell wall formation or the drug interaction directly with ergosterol. Since it has been shown that the...

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Bibliographic Details
Main Authors:	Talia Serseg, Khedidja Benarous, Menaouar Serseg, Hafiz Muzzammel Rehman, Youness El Bakri, Souraya Goumri-Said
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2022-12-01
Series:	Arab Journal of Basic and Applied Sciences
Subjects:	ADMET black fungus COVID-19 docking dynamics pharmacophore
Online Access:	https://www.tandfonline.com/doi/10.1080/25765299.2022.2126588

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