Case report: Fatal cerebral herniation caused by hypoglycemic due to mistaking glibenclamide in children
In recent years, the prevalence of diabetes in China has significantly increased, and glibenclamide is widely used as a basic hypoglycemic drug in China's primary clinical practice. There are many left-behind children in the grass-roots areas in China and various dangerous incidents of children...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Behavioral Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnbeh.2023.1085258/full |
| _version_ | 1827981752481611776 |
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| author | Chunlan Song Wanyu Jia Shengli Shi Peng Li |
| author_facet | Chunlan Song Wanyu Jia Shengli Shi Peng Li |
| author_sort | Chunlan Song |
| collection | DOAJ |
| description | In recent years, the prevalence of diabetes in China has significantly increased, and glibenclamide is widely used as a basic hypoglycemic drug in China's primary clinical practice. There are many left-behind children in the grass-roots areas in China and various dangerous incidents of children taking drugs by mistake continue to occur. This article reports a case of cerebral edema and fatal cerebral hernia caused by hypoglycemia induced by mistakenly ingesting glibenclamide in a child. This is the first reported case in China of a child who died from brain herniation caused by accidental administration of glibenclamide. This case reminded that clinicians must comprehensively consider the cause of convulsions and coma in children with unknown causes, ask the history in detail and cannot ignore the risk of hypoglycemic convulsions and coma. When hypoglycemic is detected, high concentration of glucose should be given promptly to normalize blood glucose. When dealing with unexplained convulsions and comatose children, clinical pediatricians must be alert to the possibility of accidental medication. |
| first_indexed | 2024-04-09T22:14:04Z |
| format | Article |
| id | doaj.art-7d631455d41849c5a3948a0876218b57 |
| institution | Directory Open Access Journal |
| issn | 1662-5153 |
| language | English |
| last_indexed | 2024-04-09T22:14:04Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Behavioral Neuroscience |
| spelling | doaj.art-7d631455d41849c5a3948a0876218b572023-03-23T05:13:02ZengFrontiers Media S.A.Frontiers in Behavioral Neuroscience1662-51532023-03-011710.3389/fnbeh.2023.10852581085258Case report: Fatal cerebral herniation caused by hypoglycemic due to mistaking glibenclamide in childrenChunlan SongWanyu JiaShengli ShiPeng LiIn recent years, the prevalence of diabetes in China has significantly increased, and glibenclamide is widely used as a basic hypoglycemic drug in China's primary clinical practice. There are many left-behind children in the grass-roots areas in China and various dangerous incidents of children taking drugs by mistake continue to occur. This article reports a case of cerebral edema and fatal cerebral hernia caused by hypoglycemia induced by mistakenly ingesting glibenclamide in a child. This is the first reported case in China of a child who died from brain herniation caused by accidental administration of glibenclamide. This case reminded that clinicians must comprehensively consider the cause of convulsions and coma in children with unknown causes, ask the history in detail and cannot ignore the risk of hypoglycemic convulsions and coma. When hypoglycemic is detected, high concentration of glucose should be given promptly to normalize blood glucose. When dealing with unexplained convulsions and comatose children, clinical pediatricians must be alert to the possibility of accidental medication.https://www.frontiersin.org/articles/10.3389/fnbeh.2023.1085258/fullhypoglycemic comacerebral herniaglibenclamidemistakechildren |
| spellingShingle | Chunlan Song Wanyu Jia Shengli Shi Peng Li Case report: Fatal cerebral herniation caused by hypoglycemic due to mistaking glibenclamide in children Frontiers in Behavioral Neuroscience hypoglycemic coma cerebral hernia glibenclamide mistake children |
| title | Case report: Fatal cerebral herniation caused by hypoglycemic due to mistaking glibenclamide in children |
| title_full | Case report: Fatal cerebral herniation caused by hypoglycemic due to mistaking glibenclamide in children |
| title_fullStr | Case report: Fatal cerebral herniation caused by hypoglycemic due to mistaking glibenclamide in children |
| title_full_unstemmed | Case report: Fatal cerebral herniation caused by hypoglycemic due to mistaking glibenclamide in children |
| title_short | Case report: Fatal cerebral herniation caused by hypoglycemic due to mistaking glibenclamide in children |
| title_sort | case report fatal cerebral herniation caused by hypoglycemic due to mistaking glibenclamide in children |
| topic | hypoglycemic coma cerebral hernia glibenclamide mistake children |
| url | https://www.frontiersin.org/articles/10.3389/fnbeh.2023.1085258/full |
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