Stem Cell-Induced Inflammation in Cholesteatoma Is Inhibited by the TLR4 Antagonist LPS-RS

Stem Cell-Induced Inflammation in Cholesteatoma Is Inhibited by the TLR4 Antagonist LPS-RS

Cholesteatoma is a severe non-cancerous lesion of the middle ear characterized by massive inflammation, tissue destruction, and an abnormal growth of keratinized squamous epithelium. We recently demonstrated the presence of pathogenic stem cells within cholesteatoma tissue, unfortunately their poten...

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Bibliographic Details
Main Authors: Matthias Schürmann, Johannes F. W. Greiner, Verena Volland-Thurn, Felix Oppel, Christian Kaltschmidt, Holger Sudhoff, Barbara Kaltschmidt
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
cholesteatoma
stem cells
inflammation
trl4
nf-κb
lps-rs
il-6
Online Access:https://www.mdpi.com/2073-4409/9/1/199

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