Comparative assessment of strategies to identify similar ligand-binding pockets in proteins
Abstract Background Detecting similar ligand-binding sites in globally unrelated proteins has a wide range of applications in modern drug discovery, including drug repurposing, the prediction of side effects, and drug-target interactions. Although a number of techniques to compare binding pockets ha...
| Автори: | , |
|---|---|
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
BMC
2018-03-01
|
| Серія: | BMC Bioinformatics |
| Предмети: | |
| Онлайн доступ: | http://link.springer.com/article/10.1186/s12859-018-2109-2 |