The Effect of Anticoagulant in Patients with Cirrhosis Associated with Acute Portal Vein Thrombosis
The treatment of portal vein thrombosis (PVT) in patients with liver cirrhosis (LC) has been controversial, and it is generally caseand institution-dependent. The occurrence of acute or extensive PVT is critical and requires urgent treatment because it is usually accompanied by symptoms, particula...
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| Format: | Article |
| Language: | English |
| Published: |
Jin Publishing & Printing Co.
2021-09-01
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| Series: | The Korean Journal of Gastroenterology |
| Subjects: | |
| Online Access: | https://www.kjg.or.kr/journal/view.html?uid=5747&vmd=Full |
| _version_ | 1818017237199486976 |
|---|---|
| author | Hoon Gil Jo Youe Ree Kim Eun Young Cho |
| author_facet | Hoon Gil Jo Youe Ree Kim Eun Young Cho |
| author_sort | Hoon Gil Jo |
| collection | DOAJ |
| description | The treatment of portal vein thrombosis (PVT) in patients with liver cirrhosis (LC) has been controversial, and it is generally caseand
institution-dependent. The occurrence of acute or extensive PVT is critical and requires urgent treatment because it is usually
accompanied by symptoms, particularly when total occlusion occurs, causing acute decompensation of liver disease. Even in severe
cases, drug selection and treatment duration are determined based on each institution’s experience. Therefore, consistent guidelines
for the treatment of patients with LC with PVT are required. Recently, a patient with acute occlusive PVT with LC who showed signs
of acute decompensation was treated by administering low molecular weight heparin as anticoagulant therapy. After anticoagulant
treatment, the portal vein was almost completely recanalized, and the deteriorated liver function improved. In addition, the patient
recovered well and showed no recurrence of PVT for more than a year. Thus, the most recent knowledge regarding the treatment
of nonmalignant PVT in LC was reviewed along with a case report. |
| first_indexed | 2024-04-14T07:24:40Z |
| format | Article |
| id | doaj.art-7d73f8e2be4d4eb0a2abebdd2e72b344 |
| institution | Directory Open Access Journal |
| issn | 1598-9992 2233-6869 |
| language | English |
| last_indexed | 2024-04-14T07:24:40Z |
| publishDate | 2021-09-01 |
| publisher | Jin Publishing & Printing Co. |
| record_format | Article |
| series | The Korean Journal of Gastroenterology |
| spelling | doaj.art-7d73f8e2be4d4eb0a2abebdd2e72b3442022-12-22T02:06:03ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922233-68692021-09-0178317718210.4166/kjg.2021.050The Effect of Anticoagulant in Patients with Cirrhosis Associated with Acute Portal Vein ThrombosisHoon Gil Jo0 Youe Ree Kim1Eun Young Cho2https://orcid.org/0000-0003-2604-918XDepartments of Internal Medicine, Wonkwang University School of Medicine, Iksan, KoreaDepartments of Radiology, Wonkwang University School of Medicine, Iksan, KoreaDepartments of Internal Medicine, Wonkwang University School of Medicine, Iksan, KoreaThe treatment of portal vein thrombosis (PVT) in patients with liver cirrhosis (LC) has been controversial, and it is generally caseand institution-dependent. The occurrence of acute or extensive PVT is critical and requires urgent treatment because it is usually accompanied by symptoms, particularly when total occlusion occurs, causing acute decompensation of liver disease. Even in severe cases, drug selection and treatment duration are determined based on each institution’s experience. Therefore, consistent guidelines for the treatment of patients with LC with PVT are required. Recently, a patient with acute occlusive PVT with LC who showed signs of acute decompensation was treated by administering low molecular weight heparin as anticoagulant therapy. After anticoagulant treatment, the portal vein was almost completely recanalized, and the deteriorated liver function improved. In addition, the patient recovered well and showed no recurrence of PVT for more than a year. Thus, the most recent knowledge regarding the treatment of nonmalignant PVT in LC was reviewed along with a case report.https://www.kjg.or.kr/journal/view.html?uid=5747&vmd=Fullliver cirrhosisportal veinvenous thrombosisanticoagulants |
| spellingShingle | Hoon Gil Jo Youe Ree Kim Eun Young Cho The Effect of Anticoagulant in Patients with Cirrhosis Associated with Acute Portal Vein Thrombosis The Korean Journal of Gastroenterology liver cirrhosis portal vein venous thrombosis anticoagulants |
| title | The Effect of Anticoagulant in Patients with Cirrhosis Associated with Acute Portal Vein Thrombosis |
| title_full | The Effect of Anticoagulant in Patients with Cirrhosis Associated with Acute Portal Vein Thrombosis |
| title_fullStr | The Effect of Anticoagulant in Patients with Cirrhosis Associated with Acute Portal Vein Thrombosis |
| title_full_unstemmed | The Effect of Anticoagulant in Patients with Cirrhosis Associated with Acute Portal Vein Thrombosis |
| title_short | The Effect of Anticoagulant in Patients with Cirrhosis Associated with Acute Portal Vein Thrombosis |
| title_sort | effect of anticoagulant in patients with cirrhosis associated with acute portal vein thrombosis |
| topic | liver cirrhosis portal vein venous thrombosis anticoagulants |
| url | https://www.kjg.or.kr/journal/view.html?uid=5747&vmd=Full |
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