Serum dihydroceramides correlate with insulin sensitivity in humans and decrease insulin sensitivity in vitro

Serum dihydroceramides correlate with insulin sensitivity in humans and decrease insulin sensitivity in vitro

Serum ceramides, especially C16:0 and C18:0 species, are linked to CVD risk and insulin resistance, but details of this association are not well understood. We performed this study to quantify a broad range of serum sphingolipids in individuals spanning the physiologic range of insulin sensitivity a...

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Bibliographic Details
Main Authors: Simona Zarini, Joseph T. Brozinick, Karin A. Zemski Berry, Amanda Garfield, Leigh Perreault, Anna Kerege, Hai Hoang Bui, Phil Sanders, Parker Siddall, Ming Shang Kuo, Bryan C. Bergman
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Journal of Lipid Research
Subjects:
sphingolipids
circulating ceramides
serum
insulin resistance
lipidomics
CVD
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227522001031

Internet

http://www.sciencedirect.com/science/article/pii/S0022227522001031

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