Serum dihydroceramides correlate with insulin sensitivity in humans and decrease insulin sensitivity in vitro
Serum ceramides, especially C16:0 and C18:0 species, are linked to CVD risk and insulin resistance, but details of this association are not well understood. We performed this study to quantify a broad range of serum sphingolipids in individuals spanning the physiologic range of insulin sensitivity a...
Main Authors: | Simona Zarini, Joseph T. Brozinick, Karin A. Zemski Berry, Amanda Garfield, Leigh Perreault, Anna Kerege, Hai Hoang Bui, Phil Sanders, Parker Siddall, Ming Shang Kuo, Bryan C. Bergman |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-10-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227522001031 |
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