The Effect Untreated Right Subclinical Varicocele On The Outcomes Of Contralateral Left Clinical Varicocelectomy İn İnfertile Patients.
Purpose: The management of infertile patients with unilateral subclinical varicocele (SCV) and contralateral clinical varicocele (CV) remains controversial. We aimed to evaluate the effect of untreated SCV on the outcome of contralateral clinical varicocelectomy in infertile patients with oligoasth...
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PAGEPress Publications
2024-01-01
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| Series: | Archivio Italiano di Urologia e Andrologia |
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| Online Access: | https://www.pagepressjournals.org/index.php/aiua/article/view/12128 |
| _version_ | 1797367900493840384 |
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| author | Murat Topcuoğlu Sevgin Yılmaz Murat Çakan Murat Uçar Ali Akkoç |
| author_facet | Murat Topcuoğlu Sevgin Yılmaz Murat Çakan Murat Uçar Ali Akkoç |
| author_sort | Murat Topcuoğlu |
| collection | DOAJ |
| description |
Purpose: The management of infertile patients with unilateral subclinical varicocele (SCV) and contralateral clinical varicocele (CV) remains controversial. We aimed to evaluate the effect of untreated SCV on the outcome of contralateral clinical varicocelectomy in infertile patients with oligoasthenozoospermia (OA).
Materials and Methods: Infertile patients with the diagnosis of OA who underwent left varicocelectomy were retrospectively evaluated. While all patients in the study had left clinical varicocele (LCV), some patients had concomitant right SCV. Patients were divided into two groups according to the presence or absence of a right SCV accompanying LCV as group 1; (LCV n=104) or group 2; (LCV with right SCV, n=74). Patients were evaluated with spermiogram parameters, pregnancy rates and serum levels of follicle stimulating hormone, luteinizing hormone, total testosterone at the first year of the follow-up.
Results: The mean sperm concentration increased significantly in both groups. However, group 1 showed significantly greater improvement than group 2. The ratio of progressive motile sperm in group 1 was increased significantly whereas no significant change was shown in group 2. Both the spontaneous pregnancy rate and the pregnancy rate with ART were statistically lower in the group of patients with right SCV. No statistically significant difference were detected in serum hormone levels in both groups after varicocelectomy operations.
Conclusion: Untreated right SCV may have adverse impact on the outcomes of left clinical varicocelectomy. In this context, the right testis can be considered in terms of treatment in patients with right SCV accompanying left CV.
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| first_indexed | 2024-03-08T17:24:46Z |
| format | Article |
| id | doaj.art-7d81f296a995424ea3540dfe5654ec03 |
| institution | Directory Open Access Journal |
| issn | 1124-3562 2282-4197 |
| language | English |
| last_indexed | 2024-03-08T17:24:46Z |
| publishDate | 2024-01-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Archivio Italiano di Urologia e Andrologia |
| spelling | doaj.art-7d81f296a995424ea3540dfe5654ec032024-01-02T23:07:30ZengPAGEPress PublicationsArchivio Italiano di Urologia e Andrologia1124-35622282-41972024-01-0195410.4081/aiua.2023.12128The Effect Untreated Right Subclinical Varicocele On The Outcomes Of Contralateral Left Clinical Varicocelectomy İn İnfertile Patients.Murat Topcuoğlu0Sevgin Yılmaz1Murat Çakan2Murat Uçar3Ali Akkoç4Alanya Alaaddin Keykubat UniversityDepartment of Urology, University of Health Sciences Dıskapı Training And Research Department of Urology, University of Health Sciences Dıskapı Training And Research Hospital, Ankara, TurkeyDepartment of Urology, Faculty of Medicine, Alanya Alaaddin Keykubat University, Alanya ,TurkeyDepartment of Urology, Faculty of Medicine, Alanya Alaaddin Keykubat University, Alanya ,Turkey Purpose: The management of infertile patients with unilateral subclinical varicocele (SCV) and contralateral clinical varicocele (CV) remains controversial. We aimed to evaluate the effect of untreated SCV on the outcome of contralateral clinical varicocelectomy in infertile patients with oligoasthenozoospermia (OA). Materials and Methods: Infertile patients with the diagnosis of OA who underwent left varicocelectomy were retrospectively evaluated. While all patients in the study had left clinical varicocele (LCV), some patients had concomitant right SCV. Patients were divided into two groups according to the presence or absence of a right SCV accompanying LCV as group 1; (LCV n=104) or group 2; (LCV with right SCV, n=74). Patients were evaluated with spermiogram parameters, pregnancy rates and serum levels of follicle stimulating hormone, luteinizing hormone, total testosterone at the first year of the follow-up. Results: The mean sperm concentration increased significantly in both groups. However, group 1 showed significantly greater improvement than group 2. The ratio of progressive motile sperm in group 1 was increased significantly whereas no significant change was shown in group 2. Both the spontaneous pregnancy rate and the pregnancy rate with ART were statistically lower in the group of patients with right SCV. No statistically significant difference were detected in serum hormone levels in both groups after varicocelectomy operations. Conclusion: Untreated right SCV may have adverse impact on the outcomes of left clinical varicocelectomy. In this context, the right testis can be considered in terms of treatment in patients with right SCV accompanying left CV. https://www.pagepressjournals.org/index.php/aiua/article/view/12128infertilityVaricocele bilateralityVaricocele; Subclinical; Total motile sperm count (TMSC); Infertility; Bilateral |
| spellingShingle | Murat Topcuoğlu Sevgin Yılmaz Murat Çakan Murat Uçar Ali Akkoç The Effect Untreated Right Subclinical Varicocele On The Outcomes Of Contralateral Left Clinical Varicocelectomy İn İnfertile Patients. Archivio Italiano di Urologia e Andrologia infertility Varicocele bilaterality Varicocele; Subclinical; Total motile sperm count (TMSC); Infertility; Bilateral |
| title | The Effect Untreated Right Subclinical Varicocele On The Outcomes Of Contralateral Left Clinical Varicocelectomy İn İnfertile Patients. |
| title_full | The Effect Untreated Right Subclinical Varicocele On The Outcomes Of Contralateral Left Clinical Varicocelectomy İn İnfertile Patients. |
| title_fullStr | The Effect Untreated Right Subclinical Varicocele On The Outcomes Of Contralateral Left Clinical Varicocelectomy İn İnfertile Patients. |
| title_full_unstemmed | The Effect Untreated Right Subclinical Varicocele On The Outcomes Of Contralateral Left Clinical Varicocelectomy İn İnfertile Patients. |
| title_short | The Effect Untreated Right Subclinical Varicocele On The Outcomes Of Contralateral Left Clinical Varicocelectomy İn İnfertile Patients. |
| title_sort | effect untreated right subclinical varicocele on the outcomes of contralateral left clinical varicocelectomy in infertile patients |
| topic | infertility Varicocele bilaterality Varicocele; Subclinical; Total motile sperm count (TMSC); Infertility; Bilateral |
| url | https://www.pagepressjournals.org/index.php/aiua/article/view/12128 |
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