Chitosan oligosaccharide activates brown adipose tissue by modulating the gut microbiota and bile acid pathways based on faecal microbiota transplantation

Chitosan oligosaccharide activates brown adipose tissue by modulating the gut microbiota and bile acid pathways based on faecal microbiota transplantation

Objective: To study the effect of chitosan oligosaccharide with a molecular weight ≤3000 Da (COSM) on the energy metabolism of obese mice after faecal bacteria transplantation. Methods: A pseudo-germ-free obese mouse model was established. 16S rRNA was used to analyse the microflora of the caecal co...

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Bibliographic Details
Main Authors: Weijun Lun, Jingwen Zhou, Yan Bai, Qishi Che, Hua Cao, Jiao Guo, Zhengquan Su
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Journal of Functional Foods
Subjects:
Obesity
Chitosan oligosaccharide
Faecal microbiota transplantation
Intestinal flora
TGR5
Brown adipose tissue
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623003316

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