GLOBAL COMPARATIVE ANTITHROMBIN-FIELD STUDY: IMPACT OF LABORATORY ASSAY VARIABILITY ON THE ASSESSMENT OF ANTITHROMBIN ACTIVITY MEASUREMENT

Objectives: Fitusiran is an investigational, subcutaneous small interfering RNA therapeutic in development for hemophilia A and B, with and without inhibitors that aims to rebalance hemostasis by targeting antithrombin (AT) mRNA to lower AT levels and restore sufficient thrombin generation. To furth...

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Main Authors: E Seth-Chhabra, A Sadeghi-Khomami, Mingjie-Liu, Guy-Young, S W-Pipe, MC Ozelo, C Le-Camus, M Toh, SA Lima-Montalvao, Marek-Demissie
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Hematology, Transfusion and Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2531137924005923