High CD8+ T cell activation marks a less differentiated HIV-1 specific CD8+ T cell response that is not altered by suppression of viral replication.
The relationship of elevated T cell activation to altered T cell differentiation profiles, each defining features of HIV-1 infection, has not been extensively explored. We hypothesized that anti-retroviral suppression of T cell activation levels would lead to alterations in the T cell differentiatio...
Κύριοι συγγραφείς: | , , , , , , , , |
---|---|
Μορφή: | Άρθρο |
Γλώσσα: | English |
Έκδοση: |
Public Library of Science (PLoS)
2009-01-01
|
Σειρά: | PLoS ONE |
Διαθέσιμο Online: | http://europepmc.org/articles/PMC2634967?pdf=render |