Modification of collagen with proanthocyanidins by mimicking the bridging role of glycosaminoglycans for dentine remineralization

Modification of collagen with proanthocyanidins by mimicking the bridging role of glycosaminoglycans for dentine remineralization

Glycosaminoglycans (GAGs) form bridging cross-bands that maintain structural integrity of collagen in the organic matrix of dentine. In dentine caries, proteolytic enzymes appeared to trigger GAGs bridge degradation, followed by breakdown of the collagen network, imposing critical limitations on den...

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Bibliographic Details
Main Authors: Ye Zhang, Ying Huang, Yanyun Pang, Zihui Zhu, Yuchen Zhang, Qing Liu, Xu Zhang, Ying Liu
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Materials & Design
Subjects:
Biomineralization
Glycosaminoglycans
Proanthocyanidins
Collagen
Dentine caries
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127521006225

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