The roles of NANOG in tumorigenesis
The pluripotency factor Nanog is highly expressed in pluripotent stem cells and certain adult stem cells, but is not expressed in normal adult cells. However, Nanog is frequently overexpressed in human cancers. Here, we discuss the distinct oncogenic roles of Nanog at various stages of tumorigenesis...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2018-05-01
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| Series: | Molecular & Cellular Oncology |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/23723556.2015.1074334 |
| _version_ | 1797677219218194432 |
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| author | Jinchul Kim Stefan Yu Yang Xu |
| author_facet | Jinchul Kim Stefan Yu Yang Xu |
| author_sort | Jinchul Kim |
| collection | DOAJ |
| description | The pluripotency factor Nanog is highly expressed in pluripotent stem cells and certain adult stem cells, but is not expressed in normal adult cells. However, Nanog is frequently overexpressed in human cancers. Here, we discuss the distinct oncogenic roles of Nanog at various stages of tumorigenesis. |
| first_indexed | 2024-03-11T22:41:55Z |
| format | Article |
| id | doaj.art-7d8578bf7f4d4805bbfa60a64652c121 |
| institution | Directory Open Access Journal |
| issn | 2372-3556 |
| language | English |
| last_indexed | 2024-03-11T22:41:55Z |
| publishDate | 2018-05-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Molecular & Cellular Oncology |
| spelling | doaj.art-7d8578bf7f4d4805bbfa60a64652c1212023-09-22T09:10:57ZengTaylor & Francis GroupMolecular & Cellular Oncology2372-35562018-05-015310.1080/23723556.2015.10743341074334The roles of NANOG in tumorigenesisJinchul Kim0Stefan Yu1Yang Xu2Cancer Research Institute, Southern Medical UniversityDivision of Biological Sciences, University of CaliforniaCancer Research Institute, Southern Medical UniversityThe pluripotency factor Nanog is highly expressed in pluripotent stem cells and certain adult stem cells, but is not expressed in normal adult cells. However, Nanog is frequently overexpressed in human cancers. Here, we discuss the distinct oncogenic roles of Nanog at various stages of tumorigenesis.http://dx.doi.org/10.1080/23723556.2015.1074334differentiationnanogp53tumorigenesis |
| spellingShingle | Jinchul Kim Stefan Yu Yang Xu The roles of NANOG in tumorigenesis Molecular & Cellular Oncology differentiation nanog p53 tumorigenesis |
| title | The roles of NANOG in tumorigenesis |
| title_full | The roles of NANOG in tumorigenesis |
| title_fullStr | The roles of NANOG in tumorigenesis |
| title_full_unstemmed | The roles of NANOG in tumorigenesis |
| title_short | The roles of NANOG in tumorigenesis |
| title_sort | roles of nanog in tumorigenesis |
| topic | differentiation nanog p53 tumorigenesis |
| url | http://dx.doi.org/10.1080/23723556.2015.1074334 |
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