Long time immunogenicity of measles vaccine in the vaccination era: An open question
After WHO European Region determined the 2005 – 2010 Strategic Plan for measles elimination, the number of reported measles cases in Europe fell dramatically. This decrease is related to the vaccination strategy carried out by European countries. This extensive immunization strategy changes the epid...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2017-01-01
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| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2016.1227519 |
| _version_ | 1827807739649196032 |
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| author | Maria Serena Gallone Cinzia Germinario Angela Larocca Silvio Tafuri |
| author_facet | Maria Serena Gallone Cinzia Germinario Angela Larocca Silvio Tafuri |
| author_sort | Maria Serena Gallone |
| collection | DOAJ |
| description | After WHO European Region determined the 2005 – 2010 Strategic Plan for measles elimination, the number of reported measles cases in Europe fell dramatically. This decrease is related to the vaccination strategy carried out by European countries. This extensive immunization strategy changes the epidemiological patter and could influence the effectiveness and the long-time immunogenicity of the vaccine. To evaluate the long-time immunogenicity of the measles vaccine in the vaccination era, a pilot study among vaccinated blood donors in Apulia was designed. Of 174 enrolled patients, 93.7% presented an anti-measles IgG titer positive. GMT seems to increase by age (p = 0.001). The GMT seems to increase by age and this could be related to the exposition to natural boosters, that was more probable before the beginning of universal mass vaccination against measles. Future studies have to focus the correlation between GMT and age. |
| first_indexed | 2024-03-11T22:01:47Z |
| format | Article |
| id | doaj.art-7d89cc4ccdf14093bd620bfe687d04eb |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T22:01:47Z |
| publishDate | 2017-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-7d89cc4ccdf14093bd620bfe687d04eb2023-09-25T11:00:54ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2017-01-0113111711910.1080/21645515.2016.12275191227519Long time immunogenicity of measles vaccine in the vaccination era: An open questionMaria Serena Gallone0Cinzia Germinario1Angela Larocca2Silvio Tafuri3Aldo Moro University of BariAldo Moro University of BariPoliclinico General HospitalAldo Moro University of BariAfter WHO European Region determined the 2005 – 2010 Strategic Plan for measles elimination, the number of reported measles cases in Europe fell dramatically. This decrease is related to the vaccination strategy carried out by European countries. This extensive immunization strategy changes the epidemiological patter and could influence the effectiveness and the long-time immunogenicity of the vaccine. To evaluate the long-time immunogenicity of the measles vaccine in the vaccination era, a pilot study among vaccinated blood donors in Apulia was designed. Of 174 enrolled patients, 93.7% presented an anti-measles IgG titer positive. GMT seems to increase by age (p = 0.001). The GMT seems to increase by age and this could be related to the exposition to natural boosters, that was more probable before the beginning of universal mass vaccination against measles. Future studies have to focus the correlation between GMT and age.http://dx.doi.org/10.1080/21645515.2016.1227519anti-measles igggeometric mean titermeasles eliminationvaccination strategy |
| spellingShingle | Maria Serena Gallone Cinzia Germinario Angela Larocca Silvio Tafuri Long time immunogenicity of measles vaccine in the vaccination era: An open question Human Vaccines & Immunotherapeutics anti-measles igg geometric mean titer measles elimination vaccination strategy |
| title | Long time immunogenicity of measles vaccine in the vaccination era: An open question |
| title_full | Long time immunogenicity of measles vaccine in the vaccination era: An open question |
| title_fullStr | Long time immunogenicity of measles vaccine in the vaccination era: An open question |
| title_full_unstemmed | Long time immunogenicity of measles vaccine in the vaccination era: An open question |
| title_short | Long time immunogenicity of measles vaccine in the vaccination era: An open question |
| title_sort | long time immunogenicity of measles vaccine in the vaccination era an open question |
| topic | anti-measles igg geometric mean titer measles elimination vaccination strategy |
| url | http://dx.doi.org/10.1080/21645515.2016.1227519 |
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