Temporal trends in anxiety and depression prevalence and their association with adverse outcomes in patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease in Beijing, China, from 2004 to 2020
AimsTo investigate the temporal trend in anxiety and/or depression prevalence in patients hospitalized for acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in Beijing and their association with adverse outcomes.Materials and methodsHospital admission records from 2004 to 2020 wit...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.996451/full |
| _version_ | 1828337907087179776 |
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| author | Lin Feng Jiachen Li Xiaoshuang Lv Shuilian Chu Changwei Li Ruiyuan Zhang Xi Cao Lirong Liang |
| author_facet | Lin Feng Jiachen Li Xiaoshuang Lv Shuilian Chu Changwei Li Ruiyuan Zhang Xi Cao Lirong Liang |
| author_sort | Lin Feng |
| collection | DOAJ |
| description | AimsTo investigate the temporal trend in anxiety and/or depression prevalence in patients hospitalized for acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in Beijing and their association with adverse outcomes.Materials and methodsHospital admission records from 2004 to 2020 with a primary discharge diagnosis of AECOPD were retrieved from Beijing Public Health Information Centre database. The anxiety and depression were identified from discharge diagnoses of each record. Joinpoint regression was used to analyze the temporal trend and calculate the annual percentage change (APC) for the prevalence of anxiety and/or depression. Generalized linear model was used to analyze the associations between anxiety and/or depression and patients’ adverse outcomes.ResultsA total of 382,125 records were included, most of which were male (66.0%) and aged ≥ 75 years (59.7%). Three segments in the temporal trend were observed, with a mild increase during 2004–2009 (APC: 5.9%, 95% CI: -14.9 to 31.7%), followed by a sharply increase during 2009–2012 (APC: 60.4%, 95% CI: 10.6 to 132.7%), then stabilized at about 3% during 2012–2020 (APC: 1.9%, 95% CI: -0.4 to 4.3%). On average, anxiety, and/or depression was more prevalent in females, the aged and those admitted in secondary hospitals (all P < 0.001). Patients with anxiety and/or depression had lower in-hospital mortality (IHM) (OR = 0.74, 95% CI: 0.63–0.88), but longer hospital stay (OR = 1.10, 95% CI: 1.07–1.13), more medical costs (OR = 1.12, 95% CI: 1.08–1.17) and higher risks of readmission for AECOPD at 30-, 90-, 180-day, and 1-year (ORs ranged from 1.22 to 1.51).ConclusionThe prevalence of anxiety and/or depression in patients hospitalized for AECOPD in Beijing stabilized at approximately 3% after 2012. Anxiety and/or depression is associated with a heavier burden on patients, health care, and medical insurance systems. Appropriate diagnosis and effective treatment of anxiety and depression is crucial for patients with AECOPD. |
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| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-04-13T22:21:13Z |
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| spelling | doaj.art-7d8ba192306c48359da5fa6cff6aa37f2022-12-22T02:27:15ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402022-10-011310.3389/fpsyt.2022.996451996451Temporal trends in anxiety and depression prevalence and their association with adverse outcomes in patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease in Beijing, China, from 2004 to 2020Lin Feng0Jiachen Li1Xiaoshuang Lv2Shuilian Chu3Changwei Li4Ruiyuan Zhang5Xi Cao6Lirong Liang7Department of Clinical Epidemiology, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, ChinaDepartment of Clinical Epidemiology, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, ChinaDepartment of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, ChinaDepartment of Clinical Epidemiology, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, ChinaDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, United StatesDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, United StatesDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, United StatesDepartment of Clinical Epidemiology, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, ChinaAimsTo investigate the temporal trend in anxiety and/or depression prevalence in patients hospitalized for acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in Beijing and their association with adverse outcomes.Materials and methodsHospital admission records from 2004 to 2020 with a primary discharge diagnosis of AECOPD were retrieved from Beijing Public Health Information Centre database. The anxiety and depression were identified from discharge diagnoses of each record. Joinpoint regression was used to analyze the temporal trend and calculate the annual percentage change (APC) for the prevalence of anxiety and/or depression. Generalized linear model was used to analyze the associations between anxiety and/or depression and patients’ adverse outcomes.ResultsA total of 382,125 records were included, most of which were male (66.0%) and aged ≥ 75 years (59.7%). Three segments in the temporal trend were observed, with a mild increase during 2004–2009 (APC: 5.9%, 95% CI: -14.9 to 31.7%), followed by a sharply increase during 2009–2012 (APC: 60.4%, 95% CI: 10.6 to 132.7%), then stabilized at about 3% during 2012–2020 (APC: 1.9%, 95% CI: -0.4 to 4.3%). On average, anxiety, and/or depression was more prevalent in females, the aged and those admitted in secondary hospitals (all P < 0.001). Patients with anxiety and/or depression had lower in-hospital mortality (IHM) (OR = 0.74, 95% CI: 0.63–0.88), but longer hospital stay (OR = 1.10, 95% CI: 1.07–1.13), more medical costs (OR = 1.12, 95% CI: 1.08–1.17) and higher risks of readmission for AECOPD at 30-, 90-, 180-day, and 1-year (ORs ranged from 1.22 to 1.51).ConclusionThe prevalence of anxiety and/or depression in patients hospitalized for AECOPD in Beijing stabilized at approximately 3% after 2012. Anxiety and/or depression is associated with a heavier burden on patients, health care, and medical insurance systems. Appropriate diagnosis and effective treatment of anxiety and depression is crucial for patients with AECOPD.https://www.frontiersin.org/articles/10.3389/fpsyt.2022.996451/fullanxietydepressionchronic obstructive pulmonary diseasetemporal trendinfluenceChina |
| spellingShingle | Lin Feng Jiachen Li Xiaoshuang Lv Shuilian Chu Changwei Li Ruiyuan Zhang Xi Cao Lirong Liang Temporal trends in anxiety and depression prevalence and their association with adverse outcomes in patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease in Beijing, China, from 2004 to 2020 Frontiers in Psychiatry anxiety depression chronic obstructive pulmonary disease temporal trend influence China |
| title | Temporal trends in anxiety and depression prevalence and their association with adverse outcomes in patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease in Beijing, China, from 2004 to 2020 |
| title_full | Temporal trends in anxiety and depression prevalence and their association with adverse outcomes in patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease in Beijing, China, from 2004 to 2020 |
| title_fullStr | Temporal trends in anxiety and depression prevalence and their association with adverse outcomes in patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease in Beijing, China, from 2004 to 2020 |
| title_full_unstemmed | Temporal trends in anxiety and depression prevalence and their association with adverse outcomes in patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease in Beijing, China, from 2004 to 2020 |
| title_short | Temporal trends in anxiety and depression prevalence and their association with adverse outcomes in patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease in Beijing, China, from 2004 to 2020 |
| title_sort | temporal trends in anxiety and depression prevalence and their association with adverse outcomes in patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease in beijing china from 2004 to 2020 |
| topic | anxiety depression chronic obstructive pulmonary disease temporal trend influence China |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.996451/full |
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