Analysis and functional consequences of increased Fab-sialylation of intravenous immunoglobulin (IVIG) after lectin fractionation.

It has been proposed that the anti-inflammatory effects of intravenous immunoglobulin (IVIG) might be due to the small fraction of Fc-sialylated IgG. In this study we biochemically and functionally characterized sialic acid-enriched IgG obtained by Sambucus nigra agglutinin (SNA) lectin fractionatio...

Celý popis

Podrobná bibliografie
Hlavní autoři: Fabian Käsermann, David J Boerema, Monika Rüegsegger, Andreas Hofmann, Sandra Wymann, Adrian W Zuercher, Sylvia Miescher
Médium: Článek
Jazyk:English
Vydáno: Public Library of Science (PLoS) 2012-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC3366990?pdf=render