Experimental Evolution of Gene Expression and Plasticity in Alternative Selective Regimes.
Little is known of how gene expression and its plasticity evolves as populations adapt to different environmental regimes. Expression is expected to evolve adaptively in all populations but only those populations experiencing environmental heterogeneity are expected to show adaptive evolution of pla...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2016-09-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC5035091?pdf=render |
| _version_ | 1811232108734054400 |
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| author | Yuheng Huang Aneil F Agrawal |
| author_facet | Yuheng Huang Aneil F Agrawal |
| author_sort | Yuheng Huang |
| collection | DOAJ |
| description | Little is known of how gene expression and its plasticity evolves as populations adapt to different environmental regimes. Expression is expected to evolve adaptively in all populations but only those populations experiencing environmental heterogeneity are expected to show adaptive evolution of plasticity. We measured the transcriptome in a cadmium-enriched diet and a salt-enriched diet for experimental populations of Drosophila melanogaster that evolved for ~130 generations in one of four selective regimes: two constant regimes maintained in either cadmium or salt diets and two heterogeneous regimes that varied either temporally or spatially between the two diets. For populations evolving in constant regimes, we find a strong signature of counter-gradient evolution; the evolved expression differences between populations adapted to alternative diets is opposite to the plastic response of the ancestral population that is naïve to both diets. Based on expression patterns in the ancestral populations, we identify a set of genes for which we predict selection in heterogeneous regimes to result in increases in plasticity and we find the expected pattern. In contrast, a set of genes where we predicted reduced plasticity did not follow expectation. Nonetheless, both gene sets showed a pattern consistent with adaptive expression evolution in heterogeneous regimes, highlighting the difference between observing "optimal" plasticity and improvements in environment-specific expression. Looking across all genes, there is evidence in all regimes of differences in biased allele expression across environments ("allelic plasticity") and this is more common among genes with plasticity in total expression. |
| first_indexed | 2024-04-12T10:58:03Z |
| format | Article |
| id | doaj.art-7d90bd2ba35c4de6a51355a34c068735 |
| institution | Directory Open Access Journal |
| issn | 1553-7390 1553-7404 |
| language | English |
| last_indexed | 2024-04-12T10:58:03Z |
| publishDate | 2016-09-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Genetics |
| spelling | doaj.art-7d90bd2ba35c4de6a51355a34c0687352022-12-22T03:36:03ZengPublic Library of Science (PLoS)PLoS Genetics1553-73901553-74042016-09-01129e100633610.1371/journal.pgen.1006336Experimental Evolution of Gene Expression and Plasticity in Alternative Selective Regimes.Yuheng HuangAneil F AgrawalLittle is known of how gene expression and its plasticity evolves as populations adapt to different environmental regimes. Expression is expected to evolve adaptively in all populations but only those populations experiencing environmental heterogeneity are expected to show adaptive evolution of plasticity. We measured the transcriptome in a cadmium-enriched diet and a salt-enriched diet for experimental populations of Drosophila melanogaster that evolved for ~130 generations in one of four selective regimes: two constant regimes maintained in either cadmium or salt diets and two heterogeneous regimes that varied either temporally or spatially between the two diets. For populations evolving in constant regimes, we find a strong signature of counter-gradient evolution; the evolved expression differences between populations adapted to alternative diets is opposite to the plastic response of the ancestral population that is naïve to both diets. Based on expression patterns in the ancestral populations, we identify a set of genes for which we predict selection in heterogeneous regimes to result in increases in plasticity and we find the expected pattern. In contrast, a set of genes where we predicted reduced plasticity did not follow expectation. Nonetheless, both gene sets showed a pattern consistent with adaptive expression evolution in heterogeneous regimes, highlighting the difference between observing "optimal" plasticity and improvements in environment-specific expression. Looking across all genes, there is evidence in all regimes of differences in biased allele expression across environments ("allelic plasticity") and this is more common among genes with plasticity in total expression.http://europepmc.org/articles/PMC5035091?pdf=render |
| spellingShingle | Yuheng Huang Aneil F Agrawal Experimental Evolution of Gene Expression and Plasticity in Alternative Selective Regimes. PLoS Genetics |
| title | Experimental Evolution of Gene Expression and Plasticity in Alternative Selective Regimes. |
| title_full | Experimental Evolution of Gene Expression and Plasticity in Alternative Selective Regimes. |
| title_fullStr | Experimental Evolution of Gene Expression and Plasticity in Alternative Selective Regimes. |
| title_full_unstemmed | Experimental Evolution of Gene Expression and Plasticity in Alternative Selective Regimes. |
| title_short | Experimental Evolution of Gene Expression and Plasticity in Alternative Selective Regimes. |
| title_sort | experimental evolution of gene expression and plasticity in alternative selective regimes |
| url | http://europepmc.org/articles/PMC5035091?pdf=render |
| work_keys_str_mv | AT yuhenghuang experimentalevolutionofgeneexpressionandplasticityinalternativeselectiveregimes AT aneilfagrawal experimentalevolutionofgeneexpressionandplasticityinalternativeselectiveregimes |