Review of Canine Lymphoma Treated with Chemotherapy—Outcomes and Prognostic Factors
While canine lymphoma is a relatively common and important disease seen by veterinarians, there are limited comprehensive reviews of the literature regarding the remission and survival times following chemotherapy, and the associated prognostic factors. This comprehensive thematic review covers the...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | Veterinary Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2306-7381/10/5/342 |
| _version_ | 1797598089086763008 |
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| author | Peter Bennett Peter Williamson Rosanne Taylor |
| author_facet | Peter Bennett Peter Williamson Rosanne Taylor |
| author_sort | Peter Bennett |
| collection | DOAJ |
| description | While canine lymphoma is a relatively common and important disease seen by veterinarians, there are limited comprehensive reviews of the literature regarding the remission and survival times following chemotherapy, and the associated prognostic factors. This comprehensive thematic review covers the available veterinary literature covering treatment outcomes and identified prognostic factors. A lack of standardised approaches to evaluate and report the outcomes was identified, including factors that would alter the duration of responses by weeks, or occasionally months. After publication of the suggested reporting criteria, this has improved but is still not uniformly applied. The prognostic factors included for evaluation varied from as few as three to seventeen, with over 50 studies using only univariate analysis. Individual papers reported much longer outcomes than others, but assessing the outcomes overall, there has been minimal change over the last 40 years. This supports the belief that novel approaches for lymphoma therapy will be required to substantively improve outcomes. |
| first_indexed | 2024-03-11T03:14:28Z |
| format | Article |
| id | doaj.art-7d91ffa3b7ec4aa59d7260c6abe801f1 |
| institution | Directory Open Access Journal |
| issn | 2306-7381 |
| language | English |
| last_indexed | 2024-03-11T03:14:28Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Veterinary Sciences |
| spelling | doaj.art-7d91ffa3b7ec4aa59d7260c6abe801f12023-11-18T03:37:34ZengMDPI AGVeterinary Sciences2306-73812023-05-0110534210.3390/vetsci10050342Review of Canine Lymphoma Treated with Chemotherapy—Outcomes and Prognostic FactorsPeter Bennett0Peter Williamson1Rosanne Taylor2The Sydney School of Veterinary Science, Faculty of Science, The University of Sydney, Camperdown, NSW 2006, AustraliaThe Sydney School of Veterinary Science, Faculty of Science, The University of Sydney, Camperdown, NSW 2006, AustraliaThe Sydney School of Veterinary Science, Faculty of Science, The University of Sydney, Camperdown, NSW 2006, AustraliaWhile canine lymphoma is a relatively common and important disease seen by veterinarians, there are limited comprehensive reviews of the literature regarding the remission and survival times following chemotherapy, and the associated prognostic factors. This comprehensive thematic review covers the available veterinary literature covering treatment outcomes and identified prognostic factors. A lack of standardised approaches to evaluate and report the outcomes was identified, including factors that would alter the duration of responses by weeks, or occasionally months. After publication of the suggested reporting criteria, this has improved but is still not uniformly applied. The prognostic factors included for evaluation varied from as few as three to seventeen, with over 50 studies using only univariate analysis. Individual papers reported much longer outcomes than others, but assessing the outcomes overall, there has been minimal change over the last 40 years. This supports the belief that novel approaches for lymphoma therapy will be required to substantively improve outcomes.https://www.mdpi.com/2306-7381/10/5/342dogcancerlymphomachemotherapyprognostic factorsremission |
| spellingShingle | Peter Bennett Peter Williamson Rosanne Taylor Review of Canine Lymphoma Treated with Chemotherapy—Outcomes and Prognostic Factors Veterinary Sciences dog cancer lymphoma chemotherapy prognostic factors remission |
| title | Review of Canine Lymphoma Treated with Chemotherapy—Outcomes and Prognostic Factors |
| title_full | Review of Canine Lymphoma Treated with Chemotherapy—Outcomes and Prognostic Factors |
| title_fullStr | Review of Canine Lymphoma Treated with Chemotherapy—Outcomes and Prognostic Factors |
| title_full_unstemmed | Review of Canine Lymphoma Treated with Chemotherapy—Outcomes and Prognostic Factors |
| title_short | Review of Canine Lymphoma Treated with Chemotherapy—Outcomes and Prognostic Factors |
| title_sort | review of canine lymphoma treated with chemotherapy outcomes and prognostic factors |
| topic | dog cancer lymphoma chemotherapy prognostic factors remission |
| url | https://www.mdpi.com/2306-7381/10/5/342 |
| work_keys_str_mv | AT peterbennett reviewofcaninelymphomatreatedwithchemotherapyoutcomesandprognosticfactors AT peterwilliamson reviewofcaninelymphomatreatedwithchemotherapyoutcomesandprognosticfactors AT rosannetaylor reviewofcaninelymphomatreatedwithchemotherapyoutcomesandprognosticfactors |