Antibacterial and antifungal activities of new acylated derivatives of epigallocatechin gallate

Antibacterial and antifungal activities of new acylated derivatives of epigallocatechin gallate

(-)-Epigallocatechin-3-O-gallate (EGCG) has useful antiviral, antimicrobial, antitoxin, and antitumor properties. Previously, Mori, S. et al. (Bioorg Med Chem Lett 18:4249-4252, 2008) found that addition of long acyl chains (C16–18) to EGCG enhanced its anti-influenza virus activity up to 44-fold. T...

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Bibliographic Details
Main Authors: Yoshimi eMatsumoto, Kunihiro eKaihatsu, Kunihiko eNishino, Miho eOgawa, Nobuo eKato, Akihito eYamaguchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-02-01
Series:Frontiers in Microbiology
Subjects:
Staphylococcus aureus
mode of action
epigallocatechin gallate
fatty acid esters
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00053/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00053/full

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