| Summary: | As indicated by standards of modern dentistry, the essence of endodontic treatment is chemo-mechanical disinfection of the root canal system. The vital element of this process is the irrigation of canals with designated solutions as well as activating them. This review article summarizes various techniques of activation of irrigants for endodontic treatment such as manual activation, thermal, pressure, sonic, ultrasonic, and laser techniques in order to compare them. Results were gathered using PubMed, Scopus, Web of Science, and Google Scholar databases by searching keywords: activation, irrigation, irrigation protocols, and sodium hypochlorite.
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