Effects of Kudoa septempunctata genotype ST3 isolate from Korea on ddY suckling mice
This study investigated the effects of Kudoa septempunctata genotype ST3 spores on ddY suckling mice. Purified Kudoa septempunctata spores were administered into the stomachs of the mice at 5 × 106 or 5 × 107 spores/mouse, with inactivated Kudoa (5 × 106 spores/mouse) or vehicle as controls. No abno...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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EDP Sciences
2016-01-01
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| Series: | Parasite |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1051/parasite/2016020 |
| _version_ | 1797428606547263488 |
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| author | Jang Yeounghwan Ahn Meejung Bang Hyojin Kang Bongjo |
| author_facet | Jang Yeounghwan Ahn Meejung Bang Hyojin Kang Bongjo |
| author_sort | Jang Yeounghwan |
| collection | DOAJ |
| description | This study investigated the effects of Kudoa septempunctata genotype ST3 spores on ddY suckling mice. Purified Kudoa septempunctata spores were administered into the stomachs of the mice at 5 × 106 or 5 × 107 spores/mouse, with inactivated Kudoa (5 × 106 spores/mouse) or vehicle as controls. No abnormal clinical symptoms were observed and there were no variations in fluid accumulation ratio and cytokine gene expression in all groups. In addition, intact Kudoa spores and the 18S rDNA gene were only detected (by microscopy and quantitative PCR, respectively) in the groups administered such spores. This study thus confirms that spores from the ST3 strain of Kudoa septempunctata were excreted in the faeces without infecting the gastrointestinal tract in ddY suckling mice. |
| first_indexed | 2024-03-09T09:01:18Z |
| format | Article |
| id | doaj.art-7d9406a0f4ce4790a9076753426a285f |
| institution | Directory Open Access Journal |
| issn | 1776-1042 |
| language | English |
| last_indexed | 2024-03-09T09:01:18Z |
| publishDate | 2016-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | Parasite |
| spelling | doaj.art-7d9406a0f4ce4790a9076753426a285f2023-12-02T11:42:25ZengEDP SciencesParasite1776-10422016-01-01231810.1051/parasite/2016020parasite160015Effects of Kudoa septempunctata genotype ST3 isolate from Korea on ddY suckling miceJang YeounghwanAhn MeejungBang HyojinKang BongjoThis study investigated the effects of Kudoa septempunctata genotype ST3 spores on ddY suckling mice. Purified Kudoa septempunctata spores were administered into the stomachs of the mice at 5 × 106 or 5 × 107 spores/mouse, with inactivated Kudoa (5 × 106 spores/mouse) or vehicle as controls. No abnormal clinical symptoms were observed and there were no variations in fluid accumulation ratio and cytokine gene expression in all groups. In addition, intact Kudoa spores and the 18S rDNA gene were only detected (by microscopy and quantitative PCR, respectively) in the groups administered such spores. This study thus confirms that spores from the ST3 strain of Kudoa septempunctata were excreted in the faeces without infecting the gastrointestinal tract in ddY suckling mice.http://dx.doi.org/10.1051/parasite/2016020Kudoa septempunctataST3 genotypeFood-borne diseaseMyxozoaParalichthys olivaceussuckling mice |
| spellingShingle | Jang Yeounghwan Ahn Meejung Bang Hyojin Kang Bongjo Effects of Kudoa septempunctata genotype ST3 isolate from Korea on ddY suckling mice Parasite Kudoa septempunctata ST3 genotype Food-borne disease Myxozoa Paralichthys olivaceus suckling mice |
| title | Effects of Kudoa septempunctata genotype ST3 isolate from Korea on ddY suckling mice |
| title_full | Effects of Kudoa septempunctata genotype ST3 isolate from Korea on ddY suckling mice |
| title_fullStr | Effects of Kudoa septempunctata genotype ST3 isolate from Korea on ddY suckling mice |
| title_full_unstemmed | Effects of Kudoa septempunctata genotype ST3 isolate from Korea on ddY suckling mice |
| title_short | Effects of Kudoa septempunctata genotype ST3 isolate from Korea on ddY suckling mice |
| title_sort | effects of kudoa septempunctata genotype st3 isolate from korea on ddy suckling mice |
| topic | Kudoa septempunctata ST3 genotype Food-borne disease Myxozoa Paralichthys olivaceus suckling mice |
| url | http://dx.doi.org/10.1051/parasite/2016020 |
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