Emerging Understanding of the Mechanism of Action for Dimethyl Fumarate in the Treatment of Multiple Sclerosis

Emerging Understanding of the Mechanism of Action for Dimethyl Fumarate in the Treatment of Multiple Sclerosis

Dimethyl fumarate (DMF) is an effective treatment option for relapsing–remitting multiple sclerosis (MS), but its therapeutic mechanism of action has not been fully elucidated. A better understanding of its mechanism will allow for the development of assays to monitor its clinical efficacy and safet...

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Bibliographic Details
Main Authors: Elizabeth A. Mills, Magdalena A. Ogrodnik, Andrew Plave, Yang Mao-Draayer
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Neurology
Subjects:
BG-12
lymphopenia
inflammation
neuroprotection
antioxidant
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2018.00005/full

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