Genome-Wide DNA Methylation Patterns in Persistent Attention-Deficit/Hyperactivity Disorder and in Association With Impulsive and Callous Traits

Genome-Wide DNA Methylation Patterns in Persistent Attention-Deficit/Hyperactivity Disorder and in Association With Impulsive and Callous Traits

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that often persists into adulthood. ADHD and related personality traits, such as impulsivity and callousness, are caused by genetic and environmental factors and their interplay. Epigenetic modifications of DNA, includi...

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Bibliographic Details
Main Authors: Mandy Meijer, Marieke Klein, Eilis Hannon, Dennis van der Meer, Catharina Hartman, Jaap Oosterlaan, Dirk Heslenfeld, Pieter J. Hoekstra, Jan Buitelaar, Jonathan Mill, Barbara Franke
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Genetics
Subjects:
persistent attention-deficit/hyperactivity disorder
remittent attention-deficit/hyperactivity disorder
callous traits
impulsivity
DNA methylation
epigenome-wide association study
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00016/full

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