Prognostic value of Angiographic Perfusion Score (APS) following percutaneous interventions in acute coronary syndromes
Introduction: Identifying reperfusion and predicting post procedure risk is important following Percutaneous Coronary Interventions (PCI). An Angiographic Perfusion Score (APS) combining TIMI flow (TFG) and myocardial perfusion (TMPG) grades before and after PCI can accurately measure both epicardia...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2013-01-01
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| Series: | Indian Heart Journal |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0019483212003215 |
| _version_ | 1819093669520605184 |
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| author | V.S. Narain L. Fischer A. Puri R. Sethi S.K. Dwivedi |
| author_facet | V.S. Narain L. Fischer A. Puri R. Sethi S.K. Dwivedi |
| author_sort | V.S. Narain |
| collection | DOAJ |
| description | Introduction: Identifying reperfusion and predicting post procedure risk is important following Percutaneous Coronary Interventions (PCI). An Angiographic Perfusion Score (APS) combining TIMI flow (TFG) and myocardial perfusion (TMPG) grades before and after PCI can accurately measure both epicardial and myocardial perfusion and predict Major Adverse Cardiac Events (MACE).
Patients and methods: APS was calculated in 226 (88 ST elevation Myocardial Infarction (STEMI) and 138 Non STEMI) patients. Maximum score being 12, reperfusion was defined as failed: 0–3, partial: 4–9, and full APS: 10–12. Thirty day MACE were observed.
Results: APS identified reperfusion significantly more than TMPG alone (STEMI: 50.6% vs 11.8% (p < 0.001); Non STEMI, early reperfusion: 69.4% vs 52.8% (p < 0.01) and Non STEMI late reperfusion: 38.2% vs 7.8%; (p ≤ 0.001) respectively. A significantly lower incidence of MACE was observed in the full as compared to the failed APS group (1.8% vs 22.5%) (p < 0.001). No differences were noted between TMPG 0–2 (9.8%, 9.4%, 7.3%, respectively) (p = NS).
Conclusion: Compared to MPG alone APS detects more low risk reperfused patients, post PCI. |
| first_indexed | 2024-12-21T23:15:11Z |
| format | Article |
| id | doaj.art-7d9b73a4f0d5458a94fbd62b86627aec |
| institution | Directory Open Access Journal |
| issn | 0019-4832 |
| language | English |
| last_indexed | 2024-12-21T23:15:11Z |
| publishDate | 2013-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Indian Heart Journal |
| spelling | doaj.art-7d9b73a4f0d5458a94fbd62b86627aec2022-12-21T18:46:56ZengElsevierIndian Heart Journal0019-48322013-01-016511610.1016/j.ihj.2012.12.020Prognostic value of Angiographic Perfusion Score (APS) following percutaneous interventions in acute coronary syndromesV.S. Narain0L. Fischer1A. Puri2R. Sethi3S.K. Dwivedi4Professor, Department of Cardiology, CSM Medical University (Upgraded K.G.'s Medical University), Lucknow, Uttar Pradesh, IndiaSenior Resident, Department of Cardiology, CSM Medical University (Upgraded K.G.'s Medical University), Lucknow, Uttar Pradesh, IndiaAssistant Professor, Department of Cardiology, CSM Medical University (Upgraded K.G.'s Medical University), Lucknow, Uttar Pradesh, IndiaAssistant Professor, Department of Cardiology, CSM Medical University (Upgraded K.G.'s Medical University), Lucknow, Uttar Pradesh, IndiaProfessor, Department of Cardiology, CSM Medical University (Upgraded K.G.'s Medical University), Lucknow, Uttar Pradesh, IndiaIntroduction: Identifying reperfusion and predicting post procedure risk is important following Percutaneous Coronary Interventions (PCI). An Angiographic Perfusion Score (APS) combining TIMI flow (TFG) and myocardial perfusion (TMPG) grades before and after PCI can accurately measure both epicardial and myocardial perfusion and predict Major Adverse Cardiac Events (MACE). Patients and methods: APS was calculated in 226 (88 ST elevation Myocardial Infarction (STEMI) and 138 Non STEMI) patients. Maximum score being 12, reperfusion was defined as failed: 0–3, partial: 4–9, and full APS: 10–12. Thirty day MACE were observed. Results: APS identified reperfusion significantly more than TMPG alone (STEMI: 50.6% vs 11.8% (p < 0.001); Non STEMI, early reperfusion: 69.4% vs 52.8% (p < 0.01) and Non STEMI late reperfusion: 38.2% vs 7.8%; (p ≤ 0.001) respectively. A significantly lower incidence of MACE was observed in the full as compared to the failed APS group (1.8% vs 22.5%) (p < 0.001). No differences were noted between TMPG 0–2 (9.8%, 9.4%, 7.3%, respectively) (p = NS). Conclusion: Compared to MPG alone APS detects more low risk reperfused patients, post PCI.http://www.sciencedirect.com/science/article/pii/S0019483212003215Angiographic Perfusion ScoreTIMI perfusion gradeMajor adverse coronary eventsAcute coronary syndromes |
| spellingShingle | V.S. Narain L. Fischer A. Puri R. Sethi S.K. Dwivedi Prognostic value of Angiographic Perfusion Score (APS) following percutaneous interventions in acute coronary syndromes Indian Heart Journal Angiographic Perfusion Score TIMI perfusion grade Major adverse coronary events Acute coronary syndromes |
| title | Prognostic value of Angiographic Perfusion Score (APS) following percutaneous interventions in acute coronary syndromes |
| title_full | Prognostic value of Angiographic Perfusion Score (APS) following percutaneous interventions in acute coronary syndromes |
| title_fullStr | Prognostic value of Angiographic Perfusion Score (APS) following percutaneous interventions in acute coronary syndromes |
| title_full_unstemmed | Prognostic value of Angiographic Perfusion Score (APS) following percutaneous interventions in acute coronary syndromes |
| title_short | Prognostic value of Angiographic Perfusion Score (APS) following percutaneous interventions in acute coronary syndromes |
| title_sort | prognostic value of angiographic perfusion score aps following percutaneous interventions in acute coronary syndromes |
| topic | Angiographic Perfusion Score TIMI perfusion grade Major adverse coronary events Acute coronary syndromes |
| url | http://www.sciencedirect.com/science/article/pii/S0019483212003215 |
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