Gestagens in assisted reproductive technology programs

Background. Luteal phase (LP) drug support is an important step in assisted reproductive technology (ART) programs efficacy. Aim. To present up-to-date data on an efficacy of LP hormonal support during ART cycles as well as to conduct a comparative analysis of various gestagen drug effectiveness. Ma...

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Main Authors: Anastasia G Syrkasheva, Yana A Petrosyan, Natalia V Dolgushina
Format: Article
Language:Russian
Published: IP Berlin A.V. 2019-04-01
Series:Гинекология
Subjects:
Online Access:https://gynecology.orscience.ru/2079-5831/article/viewFile/33503/pdf
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author Anastasia G Syrkasheva
Yana A Petrosyan
Natalia V Dolgushina
author_facet Anastasia G Syrkasheva
Yana A Petrosyan
Natalia V Dolgushina
author_sort Anastasia G Syrkasheva
collection DOAJ
description Background. Luteal phase (LP) drug support is an important step in assisted reproductive technology (ART) programs efficacy. Aim. To present up-to-date data on an efficacy of LP hormonal support during ART cycles as well as to conduct a comparative analysis of various gestagen drug effectiveness. Materials and methods. To write this review domestic and foreign publications were searched in Russian and international search systems (PubMed, eLibrary, etc.) for the last 8 years. The review includs articles from peer-reviewed literature. Results. LP drug support becomes an essential step in infertility treatment in various ART programs. Although human chorionic gonadotropin drug injections in the posttransfer period leads to an activation of endogenous steroid hormones synthesis, exogenous hormones use is currently preferred because of not having a risk of ovarian hyperstimulation syndrome. Conclusions. The variety of progesterone drugs is accompanied by a lack of algorithms for their use in various clinical situations. Further studies are required to evaluate progesterone drugs efficacy for various subgroups of patients.
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spelling doaj.art-7d9c038a340446b98fbbd7114c4d78752022-12-22T01:49:08ZrusIP Berlin A.V.Гинекология2079-56962079-58312019-04-01212767910.26442/20795696.2019.2.19023830233Gestagens in assisted reproductive technology programsAnastasia G Syrkasheva0Yana A Petrosyan1Natalia V Dolgushina2V.I.Kulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyV.I.Kulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyV.I.Kulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyBackground. Luteal phase (LP) drug support is an important step in assisted reproductive technology (ART) programs efficacy. Aim. To present up-to-date data on an efficacy of LP hormonal support during ART cycles as well as to conduct a comparative analysis of various gestagen drug effectiveness. Materials and methods. To write this review domestic and foreign publications were searched in Russian and international search systems (PubMed, eLibrary, etc.) for the last 8 years. The review includs articles from peer-reviewed literature. Results. LP drug support becomes an essential step in infertility treatment in various ART programs. Although human chorionic gonadotropin drug injections in the posttransfer period leads to an activation of endogenous steroid hormones synthesis, exogenous hormones use is currently preferred because of not having a risk of ovarian hyperstimulation syndrome. Conclusions. The variety of progesterone drugs is accompanied by a lack of algorithms for their use in various clinical situations. Further studies are required to evaluate progesterone drugs efficacy for various subgroups of patients.https://gynecology.orscience.ru/2079-5831/article/viewFile/33503/pdfinfertilityassisted reproductive technologiesin vitro fertilizationgestagens
spellingShingle Anastasia G Syrkasheva
Yana A Petrosyan
Natalia V Dolgushina
Gestagens in assisted reproductive technology programs
Гинекология
infertility
assisted reproductive technologies
in vitro fertilization
gestagens
title Gestagens in assisted reproductive technology programs
title_full Gestagens in assisted reproductive technology programs
title_fullStr Gestagens in assisted reproductive technology programs
title_full_unstemmed Gestagens in assisted reproductive technology programs
title_short Gestagens in assisted reproductive technology programs
title_sort gestagens in assisted reproductive technology programs
topic infertility
assisted reproductive technologies
in vitro fertilization
gestagens
url https://gynecology.orscience.ru/2079-5831/article/viewFile/33503/pdf
work_keys_str_mv AT anastasiagsyrkasheva gestagensinassistedreproductivetechnologyprograms
AT yanaapetrosyan gestagensinassistedreproductivetechnologyprograms
AT nataliavdolgushina gestagensinassistedreproductivetechnologyprograms