Effect of Cytotoxic T-Lymphocyte Antigen-4 on the Efficacy of the Fatty Acid-Binding Protein Vaccine Against Schistosoma japonicum

Effect of Cytotoxic T-Lymphocyte Antigen-4 on the Efficacy of the Fatty Acid-Binding Protein Vaccine Against Schistosoma japonicum

The present study evaluated the impact of blocking cytotoxic T-lymphocyte antigen-4 (CTLA-4) activity on the protective effect elicited by the fatty acid binding protein (FABP) vaccine against Schistosoma japonicum infection. Mice were randomly divided into uninfected, infected control, anti-CTLA-4...

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Bibliographic Details
Main Authors: Chun-lian Tang, Qun Pan, Ya-ping Xie, Ying Xiong, Rong-hui Zhang, Jin Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
Schistosoma japonicum
fatty acid-binding protein
regulatory T cells
cytotoxic T-lymphocyte antigen-4
granuloma
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01022/full

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