Nanoparticle exposure at nanotechnology workplaces: A review

<p>Abstract</p> <p>Risk, associated with nanomaterial use, is determined by exposure and hazard potential of these materials. Both topics cannot be evaluated absolutely independently. Realistic dose concentrations should be tested based on stringent exposure assessments for the cor...

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Main Authors: Göhler Daniel, Fissan Heinz, Asbach Christof, Kuhlbusch Thomas AJ, Stintz Michael
Format: Article
Language:English
Published: BMC 2011-07-01
Series:Particle and Fibre Toxicology
Subjects:
Online Access:http://www.particleandfibretoxicology.com/content/8/1/22
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author Göhler Daniel
Fissan Heinz
Asbach Christof
Kuhlbusch Thomas AJ
Stintz Michael
author_facet Göhler Daniel
Fissan Heinz
Asbach Christof
Kuhlbusch Thomas AJ
Stintz Michael
author_sort Göhler Daniel
collection DOAJ
description <p>Abstract</p> <p>Risk, associated with nanomaterial use, is determined by exposure and hazard potential of these materials. Both topics cannot be evaluated absolutely independently. Realistic dose concentrations should be tested based on stringent exposure assessments for the corresponding nanomaterial taking into account also the environmental and product matrix. This review focuses on current available information from peer reviewed publications related to airborne nanomaterial exposure. Two approaches to derive realistic exposure values are differentiated and independently presented; those based on workplace measurements and the others based on simulations in laboratories. An assessment of the current available workplace measurement data using a matrix, which is related to nanomaterials and work processes, shows, that data are available on the likelihood of release and possible exposure. Laboratory studies are seen as an important complementary source of information on particle release processes and hence for possible exposure. In both cases, whether workplace measurements or laboratories studies, the issue of background particles is a major problem. From this review, major areas for future activities and focal points are identified.</p>
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spelling doaj.art-7d9ec3c625714046b7e61898b79ff0bf2022-12-22T01:00:19ZengBMCParticle and Fibre Toxicology1743-89772011-07-01812210.1186/1743-8977-8-22Nanoparticle exposure at nanotechnology workplaces: A reviewGöhler DanielFissan HeinzAsbach ChristofKuhlbusch Thomas AJStintz Michael<p>Abstract</p> <p>Risk, associated with nanomaterial use, is determined by exposure and hazard potential of these materials. Both topics cannot be evaluated absolutely independently. Realistic dose concentrations should be tested based on stringent exposure assessments for the corresponding nanomaterial taking into account also the environmental and product matrix. This review focuses on current available information from peer reviewed publications related to airborne nanomaterial exposure. Two approaches to derive realistic exposure values are differentiated and independently presented; those based on workplace measurements and the others based on simulations in laboratories. An assessment of the current available workplace measurement data using a matrix, which is related to nanomaterials and work processes, shows, that data are available on the likelihood of release and possible exposure. Laboratory studies are seen as an important complementary source of information on particle release processes and hence for possible exposure. In both cases, whether workplace measurements or laboratories studies, the issue of background particles is a major problem. From this review, major areas for future activities and focal points are identified.</p>http://www.particleandfibretoxicology.com/content/8/1/22Nanoobjectsnanomaterialairbornereleaseexposureworkplacehandlingprocessing
spellingShingle Göhler Daniel
Fissan Heinz
Asbach Christof
Kuhlbusch Thomas AJ
Stintz Michael
Nanoparticle exposure at nanotechnology workplaces: A review
Particle and Fibre Toxicology
Nanoobjects
nanomaterial
airborne
release
exposure
workplace
handling
processing
title Nanoparticle exposure at nanotechnology workplaces: A review
title_full Nanoparticle exposure at nanotechnology workplaces: A review
title_fullStr Nanoparticle exposure at nanotechnology workplaces: A review
title_full_unstemmed Nanoparticle exposure at nanotechnology workplaces: A review
title_short Nanoparticle exposure at nanotechnology workplaces: A review
title_sort nanoparticle exposure at nanotechnology workplaces a review
topic Nanoobjects
nanomaterial
airborne
release
exposure
workplace
handling
processing
url http://www.particleandfibretoxicology.com/content/8/1/22
work_keys_str_mv AT gohlerdaniel nanoparticleexposureatnanotechnologyworkplacesareview
AT fissanheinz nanoparticleexposureatnanotechnologyworkplacesareview
AT asbachchristof nanoparticleexposureatnanotechnologyworkplacesareview
AT kuhlbuschthomasaj nanoparticleexposureatnanotechnologyworkplacesareview
AT stintzmichael nanoparticleexposureatnanotechnologyworkplacesareview