An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene Interactions on risk of myocardial infarction: The importance of model validation

An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene Interactions on risk of myocardial infarction: The importance of model validation

<p>Abstract</p> <p>Background</p> <p>To examine interactions among the angiotensin converting enzyme (<it>ACE</it>) insertion/deletion, plasminogen activator inhibitor-1 (<it>PAI-1</it>) <it>4G/5G</it>, and tissue plasminogen activato...

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Bibliographic Details
Main Authors: Coffey Christopher S, Hebert Patricia R, Ritchie Marylyn D, Krumholz Harlan M, Gaziano J Michael, Ridker Paul M, Brown Nancy J, Vaughan Douglas E, Moore Jason H
Format: Article
Language:English
Published: BMC 2004-04-01
Series:BMC Bioinformatics
Subjects:
cross validation
epistasis
prediction error
Online Access:http://www.biomedcentral.com/1471-2105/5/49

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