Unilateral Trigeminal Sensory Neuropathy with Sjögren’s Syndrome with Liver and Renal Impairment
Liver and renal involvement is a rare event in Sjögren’s syndrome. Sjögren’s syndrome is characterized by the progressive immune-mediated destruction of epithelial tissues of the salivary and lacrimal glands. Sensory ganglionitis, accompanied by T-cell invasion, occurs in patients with Sjögren’s syn...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-09-01
|
| Series: | Neurology International |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2035-8377/13/3/45 |
| _version_ | 1797517804371443712 |
|---|---|
| author | Kana Ozasa Noboru Noma Jumi Nakata Yoshiki Imamura |
| author_facet | Kana Ozasa Noboru Noma Jumi Nakata Yoshiki Imamura |
| author_sort | Kana Ozasa |
| collection | DOAJ |
| description | Liver and renal involvement is a rare event in Sjögren’s syndrome. Sjögren’s syndrome is characterized by the progressive immune-mediated destruction of epithelial tissues of the salivary and lacrimal glands. Sensory ganglionitis, accompanied by T-cell invasion, occurs in patients with Sjögren’s syndrome, resulting in sensory neuropathy of the face or limbs. Patients are assessed by quantitative sensory testing. A 76-year-old woman presented with numbness of her left face and was subsequently diagnosed with Sjögren’s syndrome and primary biliary cirrhosis, and was found to have renal failure. Detection of her serum anti-Ro/SSA antibody was strongly positive. Shirmer’s test or a salivary volume in the gum test also showed positive results. Her somatosensory disturbance severity was higher in the trigeminal area than in the forearm, suggesting that the trigeminal nerve is more susceptible than other parts of the nervous system in patients with Sjögren’s syndrome and primary biliary cirrhosis. A simple sensory test could be performed during regular check-ups, as sensory deficits might develop after patients are diagnosed with Sjögren’s syndrome and primary biliary cirrhosis. |
| first_indexed | 2024-03-10T07:21:20Z |
| format | Article |
| id | doaj.art-7d9fc75e7ac54370896d4362a826b811 |
| institution | Directory Open Access Journal |
| issn | 2035-8377 |
| language | English |
| last_indexed | 2024-03-10T07:21:20Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Neurology International |
| spelling | doaj.art-7d9fc75e7ac54370896d4362a826b8112023-11-22T14:33:40ZengMDPI AGNeurology International2035-83772021-09-0113346446810.3390/neurolint13030045Unilateral Trigeminal Sensory Neuropathy with Sjögren’s Syndrome with Liver and Renal ImpairmentKana Ozasa0Noboru Noma1Jumi Nakata2Yoshiki Imamura3Department of Oral Diagnostic Sciences, Nihon University School of Dentistry, Tokyo 101-8310, JapanDepartment of Oral Diagnostic Sciences, Nihon University School of Dentistry, Tokyo 101-8310, JapanDivision of International Medicine, Towa Hospital, Tokyo 120-0003, JapanDepartment of Oral Diagnostic Sciences, Nihon University School of Dentistry, Tokyo 101-8310, JapanLiver and renal involvement is a rare event in Sjögren’s syndrome. Sjögren’s syndrome is characterized by the progressive immune-mediated destruction of epithelial tissues of the salivary and lacrimal glands. Sensory ganglionitis, accompanied by T-cell invasion, occurs in patients with Sjögren’s syndrome, resulting in sensory neuropathy of the face or limbs. Patients are assessed by quantitative sensory testing. A 76-year-old woman presented with numbness of her left face and was subsequently diagnosed with Sjögren’s syndrome and primary biliary cirrhosis, and was found to have renal failure. Detection of her serum anti-Ro/SSA antibody was strongly positive. Shirmer’s test or a salivary volume in the gum test also showed positive results. Her somatosensory disturbance severity was higher in the trigeminal area than in the forearm, suggesting that the trigeminal nerve is more susceptible than other parts of the nervous system in patients with Sjögren’s syndrome and primary biliary cirrhosis. A simple sensory test could be performed during regular check-ups, as sensory deficits might develop after patients are diagnosed with Sjögren’s syndrome and primary biliary cirrhosis.https://www.mdpi.com/2035-8377/13/3/45quantitative sensory testingSjögren’s syndromeanti-Ro/SSAprimary biliary cirrhosis |
| spellingShingle | Kana Ozasa Noboru Noma Jumi Nakata Yoshiki Imamura Unilateral Trigeminal Sensory Neuropathy with Sjögren’s Syndrome with Liver and Renal Impairment Neurology International quantitative sensory testing Sjögren’s syndrome anti-Ro/SSA primary biliary cirrhosis |
| title | Unilateral Trigeminal Sensory Neuropathy with Sjögren’s Syndrome with Liver and Renal Impairment |
| title_full | Unilateral Trigeminal Sensory Neuropathy with Sjögren’s Syndrome with Liver and Renal Impairment |
| title_fullStr | Unilateral Trigeminal Sensory Neuropathy with Sjögren’s Syndrome with Liver and Renal Impairment |
| title_full_unstemmed | Unilateral Trigeminal Sensory Neuropathy with Sjögren’s Syndrome with Liver and Renal Impairment |
| title_short | Unilateral Trigeminal Sensory Neuropathy with Sjögren’s Syndrome with Liver and Renal Impairment |
| title_sort | unilateral trigeminal sensory neuropathy with sjogren s syndrome with liver and renal impairment |
| topic | quantitative sensory testing Sjögren’s syndrome anti-Ro/SSA primary biliary cirrhosis |
| url | https://www.mdpi.com/2035-8377/13/3/45 |
| work_keys_str_mv | AT kanaozasa unilateraltrigeminalsensoryneuropathywithsjogrenssyndromewithliverandrenalimpairment AT noborunoma unilateraltrigeminalsensoryneuropathywithsjogrenssyndromewithliverandrenalimpairment AT juminakata unilateraltrigeminalsensoryneuropathywithsjogrenssyndromewithliverandrenalimpairment AT yoshikiimamura unilateraltrigeminalsensoryneuropathywithsjogrenssyndromewithliverandrenalimpairment |