Increased Frequency of Inter-Subtype HIV-1 Recombinants Identified by Near Full-Length Virus Sequencing in Rwandan Acute Transmission Cohorts

Increased Frequency of Inter-Subtype HIV-1 Recombinants Identified by Near Full-Length Virus Sequencing in Rwandan Acute Transmission Cohorts

Most studies of HIV-1 transmission have focused on subtypes B and C. In this study, we determined the genomic sequences of the transmitted founder (TF) viruses from acutely infected individuals enrolled between 2005 and 2011 into IAVI protocol C in Rwanda and have compared these isolates to viruses...

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Bibliographic Details
Main Authors:	Gisele Umviligihozo, Erick Muok, Emmanuel Nyirimihigo Gisa, Rui Xu, Dario Dilernia, Kimberley Herard, Heeyah Song, Qianhong Qin, Jean Bizimana, Paul Farmer, Jonathan Hare, Jill Gilmour, Susan Allen, Etienne Karita, Eric Hunter, Ling Yue
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-10-01
Series:	Frontiers in Microbiology
Subjects:	HIV-1 transmission genetic bottleneck HIV subtype inter-subtype recombination antiretroviral drug resistance mutations near full-length genome sequencing
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2021.734929/full

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