Linking protein structural and functional change to mutation using amino acid networks
The function of a protein is strongly dependent on its structure. During evolution, proteins acquire new functions through mutations in the amino-acid sequence. Given the advance in deep mutational scanning, recent findings have found functional change to be position dependent, notwithstanding the c...
Main Authors: | Cristina Sotomayor-Vivas, Enrique Hernández-Lemus, Rodrigo Dorantes-Gilardi |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782487/?tool=EBI |
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